A
A J Brent
Researcher at Nuffield Orthopaedic Centre
Publications - 2
Citations - 82
A J Brent is an academic researcher from Nuffield Orthopaedic Centre. The author has contributed to research in topics: Randomized controlled trial & Context (language use). The author has an hindex of 1, co-authored 2 publications receiving 47 citations.
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Journal ArticleDOI
Oral versus intravenous antibiotics for bone and joint infections: the OVIVA non-inferiority RCT
Matthew Scarborough,H K Li,H K Li,Ines Rombach,Rhea Zambellas,A S Walker,Martin McNally,Bridget L. Atkins,Michelle Kümin,Benjamin A. Lipsky,H Hughes,D Bose,S Warren,Damien Mack,Damien Mack,J Folb,E Moore,Neil Jenkins,Susan Hopkins,R.A. Seaton,C Hemsley,Jonathan Sandoe,I Aggarwal,S C Ellis,R K Sutherland,Claudia Geue,Nicola McMeekin,C Scarborough,John Paul,Graham S Cooke,Jennifer Bostock,E Khatamzas,N Wong,A J Brent,J Lomas,Philippa C Matthews,Philippa C Matthews,Tri Wangrangsimakul,Roger Gundle,M Rogers,Adrian Taylor,Guy E. Thwaites,Philip Bejon +42 more
TL;DR: PO antibiotic therapy is non-inferior to IV therapy when used during the first 6 weeks in the treatment for bone and joint infection, as assessed by definitive treatment failure within 1 year of randomisation.
Journal ArticleDOI
Providing an Evidence Base for Tissue Sampling and Culture Interpretation in Suspected Fracture-Related Infection.
TL;DR: In this paper, the authors evaluated the sensitivity and specificity of diagnostic cut-offs for the number of surgical specimens yielding indistinguishable microorganisms and for the total number of specimens for the diagnosis of fracture-related infection.