Showing papers by "A. K. Gupta published in 2011"

A multicentre observational study to ascertain the role of homoeopathic therapy in Urolithiasis

Abstract: Study was aimed to ascertain the role of homoeopathic medicines in Urolithiasis. A prospective, multicentre observational study was conducted by Central Council for Research in Homoeopathy (CCRH) from October 2005 to January 2010 to find the usefulness of homoeopathic medicines in cases of Urolithiasis. 901 cases were screened, out of which 311 cases were enrolled and 220 cases were analyzed in this study. The symptoms pertaining to urolithiasis were assessed before and after treatment. Pain, Dysuria and Haematuria were graded from 0-3 as per severity of complaints. Calculi were graded as per Number, Size and Position of calculi. The difference between the scores was assessed by using 'Wilcoxon sign rank test' in SPSS software (ver. 16). Out of 220 cases, there was expulsion of calculi in 106 cases (single calculus in 76 cases, multiple calculi in 30 cases) and in 114 cases, calculi remained but the symptom score reduced, indicating improvement in the case. The symptom score at baseline and after treatment was analysed and found statistically significant (P<0.005). The medicines found most useful were Lycopodium clavatum in 40.9% (n=90) cases; Sulphur in 12.3% (n=27) cases; Pulsatilla nigricans in 8.2% (n=18) cases; Nux vomica in 6.2% (n=14) cases and Cantharis vesicatoria in 5.9% (n=13) cases. Treatment with homoeopathic medicines showed positive response in dissolution/expulsion of calculi. Further validation of these results is needed by conducting randomized clinical trial.

Incidence of fractures and their management in animals: a clinical study of 77 cases

Abstract: The objective of the study was to record the incidence of fractures and the outcome of their management in different animals. The data were analysed with respect to the species, breed, sex and age of the animal, duration and cause of fracture, limb and bone involved, type of fracture and the technique of fixation. The results showed higher occurrence of fractures in young, male dogs and bovines. Intramedullary pinning was found satisfactory for fixation of long bone fractures in most of the dogs, and in large animals Plaster of Paris cast with Splint was satisfactory in closed fractures below the stifle and elbow joints.

Obstructive Urolithiasis in Small Ruminants and its Surgical management

Abstract: The study was conducted in five goats and four sheep suffering with obstructive urolithiasis. The age, duration of obstruction, castration status, obstruction degree, status of urinary bladder and urethra were recorded. The surgical techniques adopted were tube cystostomy, urethrotomy and urethral process excision. Most of the animals were aged below 6 months, uncastrated, had complete urethral obstruction and presented within 3 days of urinary obstruction. One goat had ruptured urinary bladder and two sheep had ruptured urethra. The common clinical signs were dullness, depression, frequent attempt to void urine, inappetance and vocalization. Amongst the three techniques, tube cystostomy was found effective in the management of obstructive urolithiasis in small ruminants.

Indian National Gamma Array at IUAC

Abstract: Indian National Gamma Array (INGA) is a 4π multi-detector gamma-ray spectrometer based on twenty four Compton-suppressed Clover Germanium detectors with a total photo peak efficiency ~ 5 %. INGA was designed to perform high resolution gamma-ray spectroscopy to study nuclear structure at high spins with stable ion beams at Inter University Accelerator Centre (IUAC). Description of the facility and performance of the array are presented in this paper. Since its commissioning, a number of nuclear spectroscopic investigations have been carried out using the array.

Antidiabetic activity of Bauhinia Tomentosa Linn. roots extract in alloxan induced diabetic rats

Abstract: The ethanolic extract of the roots of Bauhinia tomentosa Linn. (Family – Fabaceae) were tested for antidiabetic activity by glucose tolerance test in normal rats and alloxan induced diabetic rat. Extract was administered daily for 14 days at doses of 250 and 500 mg/kg. i.p. 5 days after alloxan injection (120mg/kg). Both of doses extract showed significant antidiabetic activity and was compared with glibenclamide (10 mg/kg). Extract with 250 mg and 500mg showed 27.6% and 40.3% decrease in blood glucose level while glibenclamide showed 44.7% decrease in blood glucose level.

Fluorotic cervical compressive myelopathy, 20 years after laminectomy: A rare event

Abstract: Background: Spinal cord compression in flourosis is a common complication. These complications are mainly due to compression of the spinal cord by thickening and ossification of posterior longitudinal ligament and ligamentum flavum. Surgical decompression is the treatment of choice for fluorotic spinal cord compression. The recurrence of spinal cord compression after surgical decompression in flourosis is a rare event. Case Description: We are presenting a case of a 63-year-old man who belonged to Kanpur, an endemic fluorosis region in India, with symptoms of cervical cord compression cranial to the operative site, 20 years after laminectomy for cervical fluorotic myelopathy. Urinary and serum fluoride levels were elevated. The patient underwent a skeletal survey: computed tomography and magnetic resonance imaging of the cervical spine showed a postoperative defect of laminectomy, osteosclerosis, osteophyte formation, calcification of the intraosseus membrane in the forearm, thickening and ossification of the posterior longitudinal ligament at C1, thickening and ossification of the residual ligamentum flavum at C1/C2, and dural calcification at the C2 vertebral level and compressive myelopathy. The patient refused surgical decompression and was managed with tizanidine HCl (an antispasticity medicine), a sublingual single night dose, 8 mg for symptomatic relief. Conclusion: The recurrence of spinal cord compression in the fluorotic spine 20 years after laminectomy is a very unusual event and hence the patient should be kept under observation for a long duration. This case report contributes to the literature associated with the management of fluorotic spine.

Effect of tree foliage supplementation to Cenchrus ciliaris hay diet on rumen microbial population, enzyme activities and water kinetics in sheep

Abstract: Four adult male sheep of local breed each with mean body weight 29.0±4.03 and 22.32±2.14 kg were fed Cenchrus ciliaris-Leucaena leucocephala (CC-LL) and Cenchrus ciliaris-Grewia optiva (CC-GO) diets separately. Grass (CC) and tree leaves (LL and GO) were fed in 75:25 proportions, respectively for 90 days on each diet. Rumen liquor samples were drawn at 0 and 4 h post feeding twice at 60 and 90 days feeding on each diet to enumerate the rumen microbes and enzymes and for water kinetics once at 90 days feeding. Total protozoa, entodiniomorphs and holotrichs counts were comparable in rumen liquor of sheep on CC-LL and CC-GO diets. Sheep rumen liquor had similar activity/number of total viable bacteria, cellulolytic and amylolytic bacteria on both diets, while proteolytic bacteria activity was higher (P 0.05) higher glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) and glutamate dehydrogenase (GDH). Sheep rumen liquor had higher (P<0.05) cellulase activity and outflow rate (l/d) on CC- LL diet. Inclusion of GO at 25% level in grass based diet of sheep produced response similar to LL on microbes number, enzyme activity and water kinetics except rumen dilution rate.