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A. L. Blum
Researcher at University Hospital of Lausanne
Publications - 140
Citations - 6675
A. L. Blum is an academic researcher from University Hospital of Lausanne. The author has contributed to research in topics: Omeprazole & Helicobacter pylori. The author has an hindex of 38, co-authored 139 publications receiving 6567 citations.
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Journal ArticleDOI
Curing Helicobacter pylori infection in patients with duodenal ulcer may provoke reflux esophagitis
TL;DR: A considerable proportion of patients with duodenal ulcer treated for H. pylori will develop reflux esophagitis; risk factors are male sex, severity of corpus gastritis, and weight gain.
Journal ArticleDOI
Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. Omeprazole plus Clarithromycin and Amoxicillin Effect One Year after Treatment (OCAY) Study Group.
A. L. Blum,Nicholas J. Talley,Colm O'Morain,S Veldhuyzen van Zanten,Joachim Labenz,Manfred Stolte,J. A. Louw,A Stubberöd,A. Theodors,M. Sundin,E. Bolling-Sternevald,Ola Junghard +11 more
TL;DR: In patients with nonulcer dyspepsia, the eradication of H. pylori infection is not likely to relieve symptoms and there were no significant differences between the groups in the quality of life after treatment.
Journal ArticleDOI
Effect of whey-based culture supernatant of Lactobacillus acidophilus (johnsonii) La1 on Helicobacter pylori infection in humans.
Pierre Michetti,Gian Dorta,P. Wiesel,Dominique Brassart,Elena F. Verdu,M. Herranz,Christian Felley,N. Porta,M. Rouvet,A. L. Blum,Irene Corthesy-Theulaz +10 more
TL;DR: La1 culture supernatant shown to be effective in vitro has a partial, acid-independent long-term suppressive effect on H. pylori in humans.
Journal ArticleDOI
Bacterial overgrowth during treatment with omeprazole compared with cimetidine: a prospective randomised double blind study.
J Thorens,F. Froehlich,Werner Schwizer,E. Saraga,J Bille,K Gyr,P. Duroux,M. Nicolet,Brigitte Pignatelli,A. L. Blum,J J Gonvers,Michael Fried +11 more
TL;DR: The results show that the incidence of gastric and duodenal bacterial overgrowth is considerably higher in patients treated with omeprazole compared with cimetidine, which can be explained by more pronounced inhibition of Gastric acid secretion.
Journal ArticleDOI
Immunization of BALB/c mice against Helicobacter felis infection with Helicobacter pylori urease
Pierre Michetti,Irene Corthesy-Theulaz,Davin Catherine,Rainer Haas,Anne-Catherine Vaney,Madeleine Heitz,Jacques Bille,Jean-Pierre Kraehenbuhl,Saraga Emilia,A. L. Blum +9 more
TL;DR: Oral immunization with H. pylori urease protects mice against H. felis infection and it is unclear whether protection depends on the development of a mononuclear inflammatory response in the gastric corpus.