D
Dominique Brassart
Researcher at Nestlé
Publications - 38
Citations - 2707
Dominique Brassart is an academic researcher from Nestlé. The author has contributed to research in topics: Lactobacillus acidophilus & Lactobacillus johnsonii. The author has an hindex of 15, co-authored 38 publications receiving 2616 citations. Previous affiliations of Dominique Brassart include University of Paris.
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Immune modulation of blood leukocytes in humans by lactic acid bacteria: criteria for strain selection.
TL;DR: Bacterial adhesion to enterocytes, fecal colonization, or both seem to be valuable selection criteria for immunomodulation, and antiinfective mechanisms of defense can be enhanced after ingestion of specific lactic acid bacteria strains.
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Bifidobacterium strains from resident infant human gastrointestinal microflora exert antimicrobial activity
Vanessa Liévin,I Peiffer,Sylvie Hudault,Florence Rochat,Dominique Brassart,Jean-Richard Neeser,Alain L. Servin +6 more
TL;DR: Several bifidobacterium strains from resident infant human gastrointestinalmicroflora exert antimicrobial activity, suggesting that they could participate in the “barrier effect” produced by the indigenous microflora.
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Adhesion of human bifidobacterial strains to cultured human intestinal epithelial cells and inhibition of enteropathogen-cell interactions
TL;DR: In this paper, 13 human bifidobacterial strains were tested for their ability to adhere to human enterocyte-like Caco-2 cells in culture, and the adhesion occurs to the apical brush border of the enterocytic Caco2 cells and to the mucus secreted by the human mucus-secreting HT29-MTX cell line.
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Effect of whey-based culture supernatant of Lactobacillus acidophilus (johnsonii) La1 on Helicobacter pylori infection in humans.
Pierre Michetti,Gian Dorta,P. Wiesel,Dominique Brassart,Elena F. Verdu,M. Herranz,Christian Felley,N. Porta,M. Rouvet,A. L. Blum,Irene Corthesy-Theulaz +10 more
TL;DR: La1 culture supernatant shown to be effective in vitro has a partial, acid-independent long-term suppressive effect on H. pylori in humans.
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The human Lactobacillus acidophilus strain LA1 secretes a nonbacteriocin antibacterial substance(s) active in vitro and in vivo
Marie-Françoise Bernet-Camard,Vanessa Liévin,Dominique Brassart,Jean-Richard Neeser,Alain L. Servin,Sylvie Hudault +5 more
TL;DR: The spent culture supernatant of strain LA1 (LA1-SCS) contained antibacterial components active against S. typhimurium infecting the cultured human intestinal Caco-2 cells, and the LA1- SCS antibacterial activity was insensitive to proteases and independent of lactic acid production.