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A. V. S. Hill
Researcher at John Radcliffe Hospital
Publications - 8
Citations - 915
A. V. S. Hill is an academic researcher from John Radcliffe Hospital. The author has contributed to research in topics: Human leukocyte antigen & Population. The author has an hindex of 8, co-authored 8 publications receiving 902 citations.
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Journal ArticleDOI
Human cerebral malaria: association with erythrocyte rosetting and lack of anti-rosetting antibodies.
TL;DR: The hypothesis that erythrocyte rosetting contributes to the pathogenesis of cerebral malaria is supported and the suggestion that anti-rosetting antibodies protect against cerebral disease is suggested.
Journal ArticleDOI
HLA class I typing by PCR: HLA-B27 and an African B27 subtype
A. V. S. Hill,Catherine E. M. Allsopp,Dominic P. Kwiatkowski,N. M. Anstey,Brian Greenwood,Andrew J. McMichael +5 more
TL;DR: It is proposed that HLA*B-2703, unlike other HLA-B27 subtypes, may not be associated with ankylosing spondylitis, thus accounting in part for the rarity of this condition in black populations.
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Genetic polymorphism within HLA-A*02: significant allelic variation revealed in different populations
P. Krausa,M. Brywka,D. A. Savage,Kam M. Hui,Michael Bunce,J. L. F. Ngai,D. L. T. Teo,Y. W. Ong,Dan H. Barouch,C. E. M. Allsop,A. V. S. Hill,Andrew J. McMichael,Julia G. Bodmer,M. J. Browning +13 more
TL;DR: The results indicate the importance of ethnic origin in terms of the expected HLA-A*02 allelic profile, and emphasize the functional significance of allele specific subtyping of HLA*02.
Journal Article
Interethnic genetic differentiation in Africa: HLA class I antigens in The Gambia.
Catherine E. M. Allsopp,R. M. Harding,Craig J. Taylor,Michael Bunce,Dominic P. Kwiatkowski,Nicholas M. Anstey,David Brewster,Andrew J. McMichael,Brian Greenwood,A. V. S. Hill +9 more
TL;DR: Serologically typed individuals from The Gambia who are representative of the major ethnic groups in the capital, Banjul, were serologically typed for HLA-A, -B, and -C antigens, finding some marked frequency differences between the ethnic groups.
Journal ArticleDOI
Sequence analysis of HLA-Bw53, a common West African allele, suggests an origin by gene conversion of HLA-B35
Catherine E. M. Allsopp,A. V. S. Hill,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski,A. Hughes,Michael Bunce,Craig J. Taylor,L. Pazmany,David Brewster,Andrew J. McMichael,Brian Greenwood,Brian Greenwood +11 more
TL;DR: The polymerase chain reaction is used to amplify cDNA from an individual homozygous for this allele and the nucleotide sequence of the polymorphic alpha 1 and alpha 2 domains are determined which suggests an origin for Hla-Bw53 involving a gene conversion of HLA-B35 by an allele containing this Bw4 sequence.