A
A Zhou
Publications - 1
Citations - 114
A Zhou is an academic researcher. The author has contributed to research in topics: Furin & Proprotein convertase 2. The author has an hindex of 1, co-authored 1 publications receiving 110 citations.
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Chromogranin A processing and secretion: specific role of endogenous and exogenous prohormone convertases in the regulated secretory pathway.
TL;DR: It is demonstrated that chromogranin A is a substrate for the endogenous endoproteases PC1 and furin in vivo, and that such processing influences its trafficking into the regulated secretory pathway; furthermore, lack of change in chromoganin B and secretogran in II cleavage after diminution of PCl suggests that the action of PC1 on chromog Granin A may be specific within the chromog Cranin/secretogranIn protein family.