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Daniel T. O'Connor

Researcher at University of San Francisco

Publications -  478
Citations -  22297

Daniel T. O'Connor is an academic researcher from University of San Francisco. The author has contributed to research in topics: Chromogranin A & Blood pressure. The author has an hindex of 74, co-authored 477 publications receiving 21106 citations. Previous affiliations of Daniel T. O'Connor include University of Massachusetts Medical School & Anschutz Medical Campus.

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Journal ArticleDOI

The Chromogranin–Secretogranin Family

TL;DR: The members of the chromogranin–secretogran in family of peptide hormones, biogenic amines, and neurotransmitters are enclosed within vesicles in the neuroendocrine system and a variety of neurons.
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Secretion of chromogranin A by peptide-producing endocrine neoplasms.

TL;DR: The elevation of plasma chromogranin A in subjects with endocrine tumors suggests that their neoplasms co-release chromog Granin A along with the usual resident hormone of the tumor, that these neoplasm could be characterized as "chromogran inomas," and that measurement of plasma ChromogranIn A may be a useful diagnostic procedure in subjectsWith endocrine tumor groups, especially multiple endocrine neoplasia.
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Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist.

TL;DR: This small domain within chromogranin A may contribute to a novel, autocrine, homeostatic (negative-feedback) mechanism controlling catecholamine release from chromaffin cells and neurons.
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Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension.

TL;DR: Hydrogen peroxide is produced in blood plasma and elevation of its level could constitute a pathogenic factor in vascular organ damage attendant upon systemic hypertension.