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Aaron Crawford
Researcher at University of Aberdeen
Publications - 3
Citations - 182
Aaron Crawford is an academic researcher from University of Aberdeen. The author has contributed to research in topics: Host-pathogen interface & Corpus albicans. The author has an hindex of 3, co-authored 3 publications receiving 135 citations.
Papers
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Journal ArticleDOI
Essential metals at the host-pathogen interface: nutritional immunity and micronutrient assimilation by human fungal pathogens.
Aaron Crawford,Duncan Wilson +1 more
TL;DR: Recent advances which have been made in the understanding of fungal iron and zinc acquisition strategies and nutritional immunity against fungal infections are discussed, and the mechanisms of micronutrient uptake by human pathogenic fungi are explored.
Journal ArticleDOI
Biphasic zinc compartmentalisation in a human fungal pathogen
Aaron Crawford,Laura E. Lehtovirta-Morley,Laura E. Lehtovirta-Morley,Omran Alamir,Maria Joanna Niemiec,Maria Joanna Niemiec,Bader Alawfi,Mohammad Alsarraf,Volha Skrahina,Anna Carolina Borges Pereira Costa,Andrew Anderson,Sujan Yellagunda,Elizabeth R. Ballou,Elizabeth R. Ballou,Bernhard Hube,Bernhard Hube,Constantin F. Urban,Duncan Wilson +17 more
TL;DR: It is shown that zinc homeostasis in a major human fungal pathogen is a multi-stage process initiated by Zrt1/Zrt2-cellular import, followed by Zrc1-dependent intracellular compartmentalisation, and, like in Saccharomyces cerevisiae, C. albicans deals with this potential threat by rapidly compartmentalising zinc within vesicular stores called zincosomes.
Book ChapterDOI
Nutritional Immunity and Fungal Pathogenesis: The Struggle for Micronutrients at the Host-Pathogen Interface.
TL;DR: In this article, the authors explore the nutritional immune mechanisms that defend the human body against fungal infections and the strategies that these important pathogens exploit to counteract nutritional immunity and thrive in the infected host.