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Aaron Joseph L. Villaraza
Researcher at University of the Philippines Diliman
Publications - 14
Citations - 830
Aaron Joseph L. Villaraza is an academic researcher from University of the Philippines Diliman. The author has contributed to research in topics: Lanthanide & Xylenol orange. The author has an hindex of 6, co-authored 13 publications receiving 748 citations. Previous affiliations of Aaron Joseph L. Villaraza include University of Manchester & National Institutes of Health.
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Journal ArticleDOI
Macromolecules, Dendrimers, and Nanomaterials in Magnetic Resonance Imaging: The Interplay between Size, Function, and Pharmacokinetics
TL;DR: In this review, small molecule agents are introduced, but focus primarily on macromolecular MR contrast agents, particularly those containing gadolinium (Gd 3+ ) that are assembled or based in part on these same small molecules.
Journal ArticleDOI
Controlled preparation of a heterometallic lanthanide complex containing different lanthanides in symmetrical binding pockets.
Louise S. Natrajan,Aaron Joseph L. Villaraza,Alan M. Kenwright,Stephen Faulkner,Stephen Faulkner +4 more
TL;DR: A heterometallic lanthanide complex has been prepared by sequential deprotection and complexation of an orthogonally protected ligand: luminescence and NMR spectroscopy have been used to probe the integrity of the complex.
Journal ArticleDOI
Synthesis and Spectroscopic Studies on Azo-Dye Derivatives of Polymetallic Lanthanide Complexes: Using Diazotization to Link Metal Complexes Together
Matteo P. Placidi,Aaron Joseph L. Villaraza,Louise S. Natrajan,Daniel Sykes,Alan M. Kenwright,Stephen Faulkner +5 more
TL;DR: Heteronuclear tetrametallic lanthanide complexes have been synthesized from stable complexes by diazotization and azo-compound formation by using Luminescence spectroscopy.
Journal ArticleDOI
A Bacterial Source for Mollusk Pyrone Polyketides
Zhenjian Lin,Joshua P. Torres,Mary Anne Ammon,Lenny Marett,Russell W. Teichert,Christopher A. Reilly,Jason C. Kwan,Ronald W. Hughen,Malem S. Flores,Ma. Diarey B. Tianero,Olivier Peraud,James E. Cox,Alan R. Light,Aaron Joseph L. Villaraza,Margo G. Haygood,Gisela P. Concepcion,Baldomero M. Olivera,Eric W. Schmidt +17 more
TL;DR: It is shown that heavily defended cone snails also occasionally contain abundant secondary metabolites, γ-pyrones known as nocapyrones, which are synthesized by symbiotic bacteria, and are active in neurological assays, revealing that mollusks with external shells are an overlooked source of secondary metabolite diversity.
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Improved speciation characteristics of PEGylated indocyanine green-labeled Panitumumab: revisiting the solution and spectroscopic properties of a near-infrared emitting anti-HER1 antibody for optical imaging of cancer
TL;DR: A water-soluble amine-reactive PEGylated analogue of near-infrared emitting dye indocyanine green was synthesized and used to label the anti-HER1 antibody panitumumab at various equivalents and competitive radioimmunoassay demonstrated that the targeting moiety of the P EGylated bioconjugates was conserved.