A
Abdullah Algaissi
Researcher at Jazan University
Publications - 40
Citations - 1894
Abdullah Algaissi is an academic researcher from Jazan University. The author has contributed to research in topics: Medicine & Antibody. The author has an hindex of 17, co-authored 32 publications receiving 1215 citations. Previous affiliations of Abdullah Algaissi include University of Texas Medical Branch & King Abdulaziz University.
Papers
More filters
Journal ArticleDOI
A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
Shuai Xia,Lei Yan,Wei Xu,Anurodh S. Agrawal,Abdullah Algaissi,Abdullah Algaissi,Chien Te K. Tseng,Qian Wang,Lanying Du,Wenjie Tan,Ian A. Wilson,Ian A. Wilson,Shibo Jiang,Shibo Jiang,Bei Yang,Lu Lu +15 more
TL;DR: Crystal structures indicated that EK1 can form a stable six-helix bundle structure with both short α-HCoV and long β-H CoV HR1s, further supporting the role of HR1 region as a viable pan-CoV target site.
Journal ArticleDOI
Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus.
Anurodh S. Agrawal,Xinrong Tao,Abdullah Algaissi,Abdullah Algaissi,Tania Garron,Krishna Narayanan,Bi Hung Peng,Robert B. Couch,Chien Te K. Tseng +8 more
TL;DR: Inactivated Mers-CoV vaccine appears to carry a hypersensitive-type lung pathology risk from MERS- coV infection that is similar to that found with inactivated SARS-Cov vaccines from SARS -CoV infection.
Journal ArticleDOI
Preparedness and response to COVID-19 in Saudi Arabia: Building on MERS experience.
TL;DR: The response of Saudi Arabia to COVID-19 pandemic is reviewed and how did the experience learned from the Middle East respiratory syndrome coronavirus (MERS-CoV) epidemic since 2012 has helped the country to be better prepared for the current CO VID-19Pandemic.
Journal ArticleDOI
Viromimetic STING Agonist-Loaded Hollow Polymeric Nanoparticles for Safe and Effective Vaccination against Middle East Respiratory Syndrome Coronavirus.
Leon Chien Wei Lin,Chen Yu Huang,Bing Yu Yao,Jung Chen Lin,Anurodh S. Agrawal,Abdullah Algaissi,Abdullah Algaissi,Bi Hung Peng,Yu Han Liu,Ping Han Huang,Rong-Huay Juang,Yuan-Chih Chang,Chien Te K. Tseng,Hui-Wen Chen,Che Ming Jack Hu +14 more
TL;DR: Together, the biocompatible hollow nanoparticle described herein provides an excellent strategy for delivering both subunit vaccine candidates and novel adjuvants, enabling accelerated development of effective and safe vaccines against emerging viral pathogens.
Journal ArticleDOI
Therapeutic use of chloroquine and hydroxychloroquine in COVID-19 and other viral infections: A narrative review.
Anwar M. Hashem,Badrah S. Alghamdi,Abdullah Algaissi,Abdullah Algaissi,Fahad S. Alshehri,Abdullah Bukhari,Mohamed A. Alfaleh,Ziad A. Memish +7 more
TL;DR: It is worth being mindful of the potential risks and strictly rational the use of these drugs in COVID-19 patients until further high quality randomized clinical trials are available to clarify their role in the treatment or prevention of CO VID-19.