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Abeer Malkawi
Researcher at Concordia University Wisconsin
Publications - 7
Citations - 189
Abeer Malkawi is an academic researcher from Concordia University Wisconsin. The author has contributed to research in topics: Metabolome & Arginine. The author has an hindex of 4, co-authored 6 publications receiving 121 citations. Previous affiliations of Abeer Malkawi include Université du Québec à Montréal & Jordan University of Science and Technology.
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Journal ArticleDOI
A targeted metabolomics approach for clinical diagnosis of inborn errors of metabolism
Minnie Jacob,Abeer Malkawi,Nour Albast,Salam Al Bougha,Andreas L. Lopata,Majed Dasouki,Anas M. Abdel Rahman,Anas M. Abdel Rahman +7 more
TL;DR: This work introduces the establishment of a comprehensive targeted metabolomics method for a panel of 220 clinically relevant metabolites using Liquid chromatography-tandem mass spectrometry (LC-MS/MS) standardized for clinical research.
Journal ArticleDOI
Metabolomics Based Profiling of Dexamethasone Side Effects in Rats.
Abeer Malkawi,Karem H. Alzoubi,Minnie Jacob,Goran Matic,Asmaa Ali,Achraf Al Faraj,Falah Almuhanna,Majed Dasouki,Anas M. Abdel Rahman,Anas M. Abdel Rahman +9 more
TL;DR: Long-term Dex therapy in rats is associated with a distinctive metabolic profile which correlates with its side effects, and metabolomics based profiling may predict Dex treatment-related side effects and may offer possible novel therapeutic interventions.
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Dexamethasone-Induced Perturbations in Tissue Metabolomics Revealed by Chemical Isotope Labeling LC-MS analysis.
Lina A. Dahabiyeh,Abeer Malkawi,Xiaohang Wang,Dilek Colak,Ahmed H. Mujamammi,Essa M Sabi,Liang Li,Majed Dasouki,Anas M. Abdel Rahman,Anas M. Abdel Rahman +9 more
TL;DR: A potential role for glutathione supplementation and dipeptide modulators as novel therapeutic interventions to mitigate the side effects induced by Dex therapy is suggested.
Journal ArticleDOI
Proteomic Analysis of Morphologically Changed Tissues after Prolonged Dexamethasone Treatment
Abeer Malkawi,Afshan Masood,Zakia Shinwari,Minnie Jacob,Hicham Benabdelkamel,Goran Matic,Falah Almuhanna,Majed Dasouki,Ayodele Alaiya,Anas M. Abdel Rahman,Anas M. Abdel Rahman +10 more
TL;DR: This study provides a comprehensive description of the organ-specific proteomic profilesand differentially altered biochemical pathways, after prolonged Dex treatement to understand the molecular basis for development of side effects.
Journal ArticleDOI
Aptamer selection and aptasensor construction for bone density biomarkers.
Raja Chinnappan,Norhan Sameh Zaghloul,Razan AlZabn,Abeer Malkawi,Anas M. Abdel Rahman,Khalid M. Abu-Salah,Mohammed Zourob +6 more
TL;DR: Specific aptamers for OC and BC were selected by the systematic evolution of ligands by exponential enrichment (SELEX) method from the pool of ssDNA library with 60 random sequences, and the binding affinity (Kd) of the selected aptasensors were evaluated against the respective biomarkers.