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Abhinandan Devaprasad
Researcher at Utrecht University
Publications - 10
Citations - 112
Abhinandan Devaprasad is an academic researcher from Utrecht University. The author has contributed to research in topics: Inflammation & Innate immune system. The author has an hindex of 4, co-authored 10 publications receiving 53 citations. Previous affiliations of Abhinandan Devaprasad include University Medical Center Utrecht.
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Journal ArticleDOI
Cytometry by time of flight identifies distinct signatures in patients with systemic sclerosis, systemic lupus erythematosus and Sjögrens syndrome.
Maarten van der Kroef,Lucas L van den Hoogen,Jorre S. Mertens,Jorre S. Mertens,Sofie L M Blokland,Scott Haskett,Abhinandan Devaprasad,Tiago Carvalheiro,Eleni Chouri,Nadia Vazirpanah,Marta Cossu,Catherina G.K. Wichers,Sandra C Silva-Cardoso,Alsya J. Affandi,Cornelis P. J. Bekker,Ana P Lopes,Maarten R Hillen,Femke Bonte-Mineur,Marc R. Kok,Lorenzo Beretta,Marzia Rossato,Marzia Rossato,Michael Mingueneau,Joel A G van Roon,Timothy R D J Radstake +24 more
TL;DR: The results justify further research into the value of cellular phenotyping as a diagnostic aid for SSc and find a strong association between the use of prednisone and alterations in B‐cell subsets.
Journal ArticleDOI
A disease-associated microRNA cluster links inflammatory pathways and an altered composition of leukocyte subsets to noninfectious uveitis
Fleurieke H. Verhagen,Cornelis P. J. Bekker,Marzia Rossato,Sanne Hiddingh,Lieuwe de Vries,Abhinandan Devaprasad,Aridaman Pandit,Jeannette Ossewaarde-van Norel,Ninette ten Dam,Maartje C. A. Moret-Pot,Saskia M. Imhof,Joke H. de Boer,Timothy R D J Radstake,Jonas J.W. Kuiper +13 more
TL;DR: A unique miRNA cluster associated with NIU that was related to changes in leukocyte subsets demonstrating systemic changes in epigenetic regulation underlying NIU is identified.
Journal ArticleDOI
CXCL4 Links Inflammation and Fibrosis by Reprogramming Monocyte-Derived Dendritic Cells in vitro.
Sandra C Silva-Cardoso,Weiyang Tao,Chiara Angiolilli,Ana P Lopes,Cornelis P. J. Bekker,Abhinandan Devaprasad,Barbara Giovannone,Jaap M van Laar,Marta Cossu,Wioleta Marut,Erik C Hack,Rob J. de Boer,Marianne Boes,Timothy R D J Radstake,Aridaman Pandit +14 more
TL;DR: This study unveils that CXCL4 acts as a key secreted factor driving innate immune training and forming the long-sought link between inflammation and fibrosis.
Journal ArticleDOI
Neutrophil GM-CSF receptor dynamics in acute lung injury.
Silvia De Alessandris,G. John Ferguson,Alison J. Dodd,Jatinder K. Juss,Abhinandan Devaprasad,Siân C. Piper,Owen Wyatt,Helen Killick,Dominic J. Corkill,E. Suzanne Cohen,Aridaman Pandit,Timothy R D J Radstake,Rosalind Simmonds,Alison M. Condliffe,Matthew A. Sleeman,Andrew S. Cowburn,Donna K. Finch,Edwin R. Chilvers +17 more
TL;DR: Neutrophilic activation via GM‐CSFR may play an important role in neutrophilic lung inflammation even in the absence of highGM‐CSF levels or GM‐ CSFRα expression, and this receptor plays a key role in ligand clearance.
Posted ContentDOI
CXCL4 links inflammation and fibrosis through transcriptional and epigenetic reprogramming of monocyte-derived cells
Sandra C Silva-Cardoso,Weiyang Tao,Chiara Angiolilli,Ana P Lopes,Cornelis P. J. Bekker,Abhinandan Devaprasad,Barbara Giovannone,van Laar J,Marta Cossu,Wioleta Marut,Erik C Hack,de Boer Rj,Marianne Boes,Trdj Radstake,Aridaman Pandit +14 more
TL;DR: CXCL4 is unveiled as a key secreted factor driving innate immune training and forming the long-sought link between inflammation and fibrosis, validating the relevance of the gene regulatory network.