scispace - formally typeset
M

Marianne Boes

Researcher at Utrecht University

Publications -  131
Citations -  15143

Marianne Boes is an academic researcher from Utrecht University. The author has contributed to research in topics: Antigen & Antigen presentation. The author has an hindex of 41, co-authored 123 publications receiving 13840 citations. Previous affiliations of Marianne Boes include Massachusetts Institute of Technology & University Medical Center Utrecht.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

CX3CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance

TL;DR: A myeloid-derived mucosal DC in mice is identified, which populates the entire lamina propria of the small intestine, and CX3CR1-dependent processes, which control host interactions of specialized DCs with commensal and pathogenic bacteria, may regulate immunological tolerance and inflammation.
Journal ArticleDOI

Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells

TL;DR: Findings indicate that CD169+ macrophages have a dual physiological function that acts as innate ‘flypaper’ by preventing the systemic spread of lymph-borne pathogens and as critical gatekeepers at the lymph–tissue interface that facilitate the recognition of particulate antigens by B cells and initiate humoral immune responses.
Journal ArticleDOI

Cathepsin B Acts as a Dominant Execution Protease in Tumor Cell Apoptosis Induced by Tumor Necrosis Factor

TL;DR: Cathepsin B, which is commonly overexpressed in human primary tumors, may have two opposing roles in malignancy, reducing it by its proapoptotic features and enhancingIt by its known facilitation of invasion.
Journal ArticleDOI

A Critical Role of Natural Immunoglobulin M in Immediate Defense Against Systemic Bacterial Infection

TL;DR: A critical role of natural IgM in the immediate defense against severe bacterial infection is demonstrated and reconstitution with a monoclonal IgM specific to phosphatidylcholine, a conserved cell membrane component, has a modest effect.