Abigail Zabron

TL;DR: A rapid and highly sensitive point-of-care lateral flow assay for phospholipase A2 (PLA2) is demonstrated in serum through the enzyme-triggered release of a new class of biotinylated multiarmed polymers from a liposome substrate, enabling the correct diagnosis of pancreatitis in diseased clinical samples against a set of healthy controls using PLA2 activity in a point of care device for the first time.

TL;DR: There remains an urgent need for new approaches and models to improve management of this insidious and devastating disease and a bedside-to-bench approach to discussing cholangiocarcinoma is taken and research opportunities for the future are outlined.

TL;DR: NGAL in bile is a novel potential biomarker to help distinguish benign from malignant biliary obstruction and its diagnostic accuracy was confirmed in the second independent validation cohort.

TL;DR: This review will discuss the immediate- and long-term success, complications and overall benefits of self-expandable metal stents (SEMSs) in malignant or benign obstruction of the oesophagus, stomach and duodenum.

TL;DR: Diagnostic sensitivity was lower than previous African studies, but still outperformed serum AFP and p-Cresol sulfate alteration is a novel finding and may indicate an altered sulfonation capacity of the liver in patients with HCC.