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Adeleye Opejin
Researcher at Saint Louis University
Publications - 9
Citations - 344
Adeleye Opejin is an academic researcher from Saint Louis University. The author has contributed to research in topics: Cellular differentiation & Glucose transporter. The author has an hindex of 6, co-authored 9 publications receiving 233 citations. Previous affiliations of Adeleye Opejin include Calvin College.
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Journal ArticleDOI
Immunomodulatory Functions of BTLA and HVEM Govern Induction of Extrathymic Regulatory T Cells and Tolerance by Dendritic Cells.
Andrew Jones,Jessica Bourque,Lindsey M. Kuehm,Adeleye Opejin,Ryan M. Teague,Cindy Gross,Daniel Hawiger +6 more
TL;DR: Dendritic cells require BTLA and CD5-dependent mechanisms to actively adjust tolerizing T cell responses under steady-state conditions and efficient induction of Treg cells was instructed by BTLA+DEC205+CD8+CD11c+ DCs and the immunomodulatory functions of BTLA.
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CD5 Instructs Extrathymic Regulatory T Cell Development in Response to Self and Tolerizing Antigens
TL;DR: It is reported that CD5, whose expression is upregulated in T cells by self and tolerizing antigens in the thymus and periphery, governed extrathymic Treg cell development and promoted T Reg cell induction by blocking mechanistic target of rapamycin (mTOR) activation.
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Peripherally Induced Tolerance Depends on Peripheral Regulatory T Cells That Require Hopx To Inhibit Intrinsic IL-2 Expression
Andrew Jones,Adeleye Opejin,Jacob G. Henderson,Cindy Gross,Rajan Jain,Jonathan A. Epstein,Richard A. Flavell,Daniel Hawiger +7 more
TL;DR: It is reported that Hopx+ pTregs converted by DCs from Hopx− T cells are indispensible to sustain tolerance that prevents autoimmune responses directed at self-Ags during experimental acute encephalomyelitis and thatHopx inhibits intrinsic IL-2 expression in pT Regs after antigenic rechallenge.
Journal ArticleDOI
Effects of cinnamaldehyde on the glucose transport activity of GLUT1.
Christina Plaisier,Alexandra Cok,Jordan L. Scott,Adeleye Opejin,Kelsey T. Bushhouse,Matthew J. Salie,Larry L. Louters +6 more
TL;DR: The results suggest that cinnamaldehyde inhibits the activation of GLUT1 by forming a covalent link to target cysteine residue/s, which suggests that cunnamaldehyde is not a major contributor to the anti-diabetic properties of cinnamon.
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Adenosine A3 agonists reverse neuropathic pain via T cell–mediated production of IL-10
Mariaconcetta Durante,Mariaconcetta Durante,Silvia Squillace,Silvia Squillace,Filomena Lauro,Filomena Lauro,Luigino Antonio Giancotti,Elisabetta Coppi,Federica Cherchi,Lorenzo Di Cesare Mannelli,Carla Ghelardini,Grant R. Kolar,Carrie Wahlman,Adeleye Opejin,Cuiying Xiao,Marc L. Reitman,Dilip K. Tosh,Daniel Hawiger,Kenneth A. Jacobson,Daniela Salvemini +19 more
TL;DR: In this article, the A3 adenosine receptor (A3AR) has emerged as a therapeutic target with A3AR agonists to tackle the global challenge of neuropathic pain, and investigation into its mode of action is essential for ongoing clinical development.