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Lorenzo Di Cesare Mannelli

Researcher at University of Florence

Publications -  408
Citations -  9400

Lorenzo Di Cesare Mannelli is an academic researcher from University of Florence. The author has contributed to research in topics: Neuropathic pain & Medicine. The author has an hindex of 41, co-authored 369 publications receiving 7006 citations. Previous affiliations of Lorenzo Di Cesare Mannelli include Cambridge University Hospitals NHS Foundation Trust & University of York.

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Menthol: a natural analgesic compound

TL;DR: Results indicate that (-)-menthol is endowed with analgesic properties mediated through a selective activation of kappa-opioid receptors.
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Renal Lesions: Characterization with Diffusion-weighted Imaging versus Contrast-enhanced MR Imaging

TL;DR: In this article, the diagnostic performance of diffusion-weighted (DW) imaging with that of contrast materialenhanced (CE) MR imaging was compared for the characterization of renal lesions, with MR follow-up and histopathologic analysis as the reference standards.
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Assessment of Tumor Necrosis of Hepatocellular Carcinoma After Chemoembolization: Diffusion-Weighted and Contrast-Enhanced MRI With Histopathologic Correlation of the Explanted Liver

TL;DR: Compared with diffusion-weighted imaging, contrast-enhanced MRI with subtraction technique had more significant correlation with the histopathologic findings in the evaluation of necrosis of HCC after TACE.
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A Smart Platform for Hyperthermia Application in Cancer Treatment: Cobalt-Doped Ferrite Nanoparticles Mineralized in Human Ferritin Cages

TL;DR: The investigation of hyperthermic properties of HFt-NPs shows that a Co doping of 5% is enough to strongly enhance the magnetic anisotropy and thus thehyperthermic efficiency with respect to the undoped sample, suggesting this system represents a promising candidate for the development of a protein-based theranostic nanoplatform.
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Oxaliplatin-induced neuropathy: oxidative stress as pathological mechanism. Protective effect of silibinin.

TL;DR: A relationship between the improvement of oxidative alterations and pain relief is established in rats treated with natural antioxidant compounds like α-tocopherol and silibinin, which could be a valid therapeutic option for chemotherapy-induced neuropathy.