Aditya Mittal

TL;DR: It is shown that vitamin C (ascorbic acid/AA) can serve as an additional signal to induce the DevR regulon and offer a new perspective on the role of nutritional factors in TB and suggest a possible role for vitamin C in TB.

TL;DR: R rigorous analyses of several thousand crystal structures of folded proteins reveal a surprisingly simple unifying principle of backbone organization in protein folding, and finds that protein folding is a direct consequence of a narrow band of stoichiometric occurrences of amino-acids in primary sequences, regardless of the size and the fold of a protein.

TL;DR: It is concluded that proteins as different as E1 and HA drive fusion through strikingly similar membrane intermediates, with the most energy-intensive stages following rather than preceding hemifusion.

TL;DR: The simple and exact equation for the permeability coefficient developed here works from start of transport to equilibrium, being valid when the commonly used approximate equation may not be, and safer to use in any context, even for single time point estimates in high-throughput permeability assays.

TL;DR: The fitted kinetic parameters show how P-gp efflux of a wide range of xenobiotics has been maximized.