Adriane R. Todeschini

TL;DR: In this paper, the synthesis and the pharmacological profile as analgesic, antiinflammatory and anti-platelet of new functionalized 2-pyridylarylhydrazone derivatives 5a-r are discussed.

TL;DR: It is demonstrated for the first time that SARS-CoV-2 in fact is able to activate NETosis in human neutrophils, and the findings indicated that this process is associated with increased levels of intracellular Reactive Oxygen Species (ROS) in neutrophilia, which plays a role in thrombosis formation.

TL;DR: This review describes three classes of glycosylation, O-GlcNAcylation, N-linked, and mucin type O-linked glycosYLation, involved in tumor progression, their biosynthesis and highlights the available inhibitors as potential anti-tumor drugs.

TL;DR: The ability of B. kururiensis to endophytically colonize rice plantlets is demonstrated for the first time, promoting both plant growth and rice grain yield and the ability of auxin production by plant-associated B.Kururiense may have a stimulatory effect on plant development, as evidenced by activation of DR5-GUS.

TL;DR: This work studied the antinociceptive activity of OEP and its fractions on the acetic acid-induced abdominal constriction and formalin assays in SW male mice and showed maximum antinOCiceptive properties with very low doses, providing a rationale for its popular use in pain disorders.