Jorgete Logullo

TL;DR: It is demonstrated for the first time that SARS-CoV-2 in fact is able to activate NETosis in human neutrophils, and the findings indicated that this process is associated with increased levels of intracellular Reactive Oxygen Species (ROS) in neutrophilia, which plays a role in thrombosis formation.

TL;DR: In this study, it was found that DH82 cells became more susceptible to T. cruzi infection when cocultured with apoptotic cells, and resistance was not related reactive oxygen species production in the system.

TL;DR: In this article, a non-polarized profile of COVID-19 patients was found to have abnormal cytokine levels upon T cell stimulation, and this hyperactive cytokine response is associated with a significantly increased frequency of late differentiated T cells with particular phenotype of effector exhausted/senescent CD28 -CD57 + cells.

TL;DR: The results show that macrophages from BALB/c mice are more susceptible to infection than macrophage from XID mice, and B-1 cell-derived phagocytes (B-1CDP cells) were more permissive to intracellular T. cruzi infection than peritoneal Macrophages.

TL;DR: In this article , the authors studied how an in vitro extracellular matrix model interferes with T. cruzi infection in macrophages, and they demonstrated that the macrophage-matrix interaction favors trypanosoma cruzi in vitro replication and the release of anti-inflammatory cytokines during macocyte infection.