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Afsun Sujayev
Researcher at Azerbaijan National Academy of Sciences
Publications - 37
Citations - 1165
Afsun Sujayev is an academic researcher from Azerbaijan National Academy of Sciences. The author has contributed to research in topics: Carbonic anhydrase & Butyrylcholinesterase. The author has an hindex of 17, co-authored 27 publications receiving 835 citations.
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Journal ArticleDOI
Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I/II inhibitory and antioxidant activities.
Emin Garibov,Parham Taslimi,Afsun Sujayev,Zeynebe Bingol,Songül Çetinkaya,İlhami Gülçin,Şükrü Beydemir,Vagif Farzaliyev,Saleh H. Alwasel,Claudiu T. Supuran +9 more
TL;DR: The antioxidant activity of the cyclic thioureas was investigated by using different in vitro antioxidant assays, including 1,1-diphenyl-2-picrylhydrazyl (DPPH·) radical scavenging, Cu2+’and Fe3+ reducing, and Fe2- chelating activities.
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Synthesis, characterization, crystal structure, electrochemical studies and biological evaluation of metal complexes with thiosemicarbazone of glyoxylic acid
Mansura Huseynova,Parham Taslimi,Ajdar Medjidov,Vagif Farzaliyev,Mahizar Aliyeva,Gulnar Gondolova,Onur Şahin,Bahattin Yalçın,Afsun Sujayev,Efe Baturhan Orman,Ali Rıza Özkaya,İlhami Gülçin +11 more
TL;DR: In this article, the thiosemicarbazone of glyoxylic acid derivatives had effective inhibition against α-glycosidase, cytosolic carbonic anhydrase I and II isoenzymes, butyrylchioxomethyl)hydrazinyl] acetic acid (H2TAA) and acetylcholinesterase.
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Synthesis of some tetrahydropyrimidine-5-carboxylates, determination of their metal chelating effects and inhibition profiles against acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase
Afsun Sujayev,Emin Garibov,Parham Taslimi,İlhami Gülçin,Sevinj Gojayeva,Vagif Farzaliyev,Saleh Alwasel,Claudiu T. Supuran +7 more
TL;DR: 2-(Methacryloyloxy)ethyl 6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate, is a cyclic urea derivative synthesized from urea, and tested in terms of the inhibition of two physiologically relevant carbonic anhydrase (CA) isozymes I and II.
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Synthesis and biological evaluation of aminomethyl and alkoxymethyl derivatives as carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase inhibitors.
İlhami Gülçin,Malahat T. Abbasova,Parham Taslimi,Zübeyir Huyut,Leyla Safarova,Afsun Sujayev,Vagif Farzaliyev,Şükrü Beydemir,Saleh Alwasel,Claudiu T. Supuran +9 more
TL;DR: Compounds containing nitrogen and sulfur atoms can be widely used in various fields such as industry, medicine, biotechnology and chemical technology and the inhibitory effects of these molecules were investigated against acetylcholinesterase, butyrylcholinersterase and carbonic anhydrase I, and II isoenzymes.
Journal ArticleDOI
Synthesis and discovery of potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and α-glycosidase enzymes inhibitors: The novel N,N'-bis-cyanomethylamine and alkoxymethylamine derivatives.
Parham Taslimi,Cuneyt Caglayan,Vagif Farzaliyev,Oruj Nabiyev,Afsun Sujayev,Fikret Türkan,Ruya Kaya,Ruya Kaya,İlhami Gülçin +8 more
TL;DR: Novel N‐bis‐cyanomethylamine and alkoxymethylamine derivatives were effective inhibitors of the α‐glycosidase, cytosolic carbonic anhydrase I and II isoforms, butyrylcholinesterase (BChE), and acetylcholinerase (AChE) with Ki values in the range of 0.15–13.31 nM.