S
Saleh Alwasel
Researcher at King Saud University
Publications - 224
Citations - 5459
Saleh Alwasel is an academic researcher from King Saud University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 33, co-authored 172 publications receiving 3401 citations. Previous affiliations of Saleh Alwasel include University of Manchester.
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Journal ArticleDOI
Antioxidant activity and phenolic compounds of ginger (Zingiber officinale Rosc.) determined by HPLC-MS/MS
Hatice Tohma,İlhami Gülçin,İlhami Gülçin,Ercan Bursal,Ahmet C. Gören,Saleh Alwasel,Ekrem Köksal +6 more
TL;DR: In this article, the authors evaluated the antioxidant properties of ginger (Zingiber officinale Rosc.) based on three parameters: the antioxidant capacity, total phenolic and flavonoid content as well as identification of phenolic acids of water extract (WEG) and ethanol extract (EEG) of ginger.
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Antioxidant activity of taxifolin: an activity–structure relationship
TL;DR: Investigation of the antioxidants and antiradical activities of taxifolin by using different in vitro bioanalytical antioxidant methods showed thatTaxifolin had marked antioxidant, reducing ability, radical scavenging and metal-chelating activities.
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Rosmarinic acid inhibits some metabolic enzymes including glutathione S-transferase, lactoperoxidase, acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase isoenzymes
İlhami Gülçin,Andrea Scozzafava,Claudiu T. Supuran,Zeynep Köksal,Fikret Türkan,Songül Çetinkaya,Zeynebe Bingol,Zübeyir Huyut,Saleh Alwasel +8 more
TL;DR: In the present study, the inhibition effects of rosmarinic acid on tumour-associated carbonic anhydrase IX and XII isoenzymes, AChE, BchE, LPO and GST enzymes were evaluated.
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Management of oxidative stress and other pathologies in Alzheimer’s disease
Miriama Simunkova,Saleh Alwasel,Ibrahim M. Alhazza,Klaudia Jomová,Vojtech Kollar,Miroslav Rusko,Marian Valko,Marian Valko +7 more
TL;DR: The aims of this review are to discuss the current therapies based on the “combination-drugs-multitargets” strategy to target multiple pathologies to block the progression of pathogenesis of AD and to establish the ideal dose to develop effective formulations to preserve bioavailability.
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The effect of caffeic acid phenethyl ester (CAPE) on metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase, and carbonic anhydrase isoenzymes I, II, IX, and XII.
İlhami Gülçin,Andrea Scozzafava,Claudiu T. Supuran,Hulya Akincioglu,Zeynep Köksal,Fikret Türkan,Saleh Alwasel +6 more
TL;DR: The inhibition effect of CAPE on human carbonic anhydrase (hCA) isoforms I, II, IX, and XII, AChE, BchE, LPO, and GST was evaluated and CAPE inhibited these enzymes with Kis in the range between micromolar to picomolar.