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Agnès Dubois
Researcher at Pasteur Institute
Publications - 26
Citations - 1045
Agnès Dubois is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Transcription factor & Homeobox protein NANOG. The author has an hindex of 10, co-authored 22 publications receiving 791 citations. Previous affiliations of Agnès Dubois include Paul Sabatier University & Epigenomics AG.
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Journal ArticleDOI
2-D structure of the A region of Xist RNA and its implication for PRC2 association.
Sylvain Maenner,Magali Blaud,Laetitia Fouillen,Anne Savoye,Virginie Marchand,Agnès Dubois,Sarah Sanglier-Cianférani,Alain Van Dorsselaer,Philippe Clerc,Philip Avner,Athanase Visvikis,Christiane Branlant +11 more
TL;DR: Structural analyses provide new insights into the folding of the A region of the Xist RNA, which plays a crucial role in X chromosome inactivation, and its mechanism of protein recruitment.
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Molecular coupling of Tsix regulation and pluripotency.
Pablo Navarro,Pablo Navarro,Andrew J. Oldfield,Andrew J. Oldfield,Julie Legoupi,Nicola Festuccia,Agnès Dubois,Mikaël Attia,Jon Schoorlemmer,Claire Rougeulle,Claire Rougeulle,Ian Chambers,Philip Avner +12 more
TL;DR: The holistic pattern of Xist/Tsix regulation by pluripotent factors that are identified suggests a general direct governance of complex epigenetic processes by the machinery dedicated to pluripotency.
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Mitotic binding of Esrrb marks key regulatory regions of the pluripotency network
Nicola Festuccia,Agnès Dubois,Sandrine Vandormael-Pournin,Elena Gallego Tejeda,Adrien Mouren,Sylvain Bessonnard,Florian Mueller,Caroline Proux,Michel Cohen-Tannoudji,Pablo Navarro +9 more
TL;DR: It is reported that Esrrb, a major pluripotency TF, remains bound to key regulatory regions during mitosis and may act as a mitotic bookmarking factor, opening another perspective to molecularly understand the role of sequence-specific TFs in the epigenetic control of self-renewal, pluripOTency and genome reprogramming.
Journal ArticleDOI
Analogue modelling of fault reactivation: tectonic inversion and oblique remobilisation of grabens
TL;DR: In this article, an analogue model of sand above a silicone layer was examined to determine the effects of normal fault reactivation, and the influence of sedimentation has been evaluated using experiments with and without sedimentation.
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The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells.
Victor Heurtier,Victor Heurtier,Nick D.L. Owens,Inma Gonzalez,Florian Mueller,Caroline Proux,Damien Mornico,Philippe Clerc,Agnès Dubois,Pablo Navarro +9 more
TL;DR: The authors show that TF Nanog utilises multiple molecular strategies to enhance embryonic stem cell self-renewal, which include regulation of chromatin accessibility in the presence of LIF or maintenance of H3K27me3 at developmental regulators in its absence.