M
Martina Deckert
Researcher at University of Bonn
Publications - 111
Citations - 7779
Martina Deckert is an academic researcher from University of Bonn. The author has contributed to research in topics: Primary central nervous system lymphoma & Diffuse large B-cell lymphoma. The author has an hindex of 40, co-authored 100 publications receiving 6357 citations. Previous affiliations of Martina Deckert include Heidelberg University.
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Journal ArticleDOI
DNA methylation-based classification of central nervous system tumours
David Capper,David Capper,David Capper,David T.W. Jones,Martin Sill,Volker Hovestadt,Daniel Schrimpf,Daniel Schrimpf,Dominik Sturm,Dominik Sturm,Christian Koelsche,Christian Koelsche,Felix Sahm,Felix Sahm,Lukas Chavez,David E. Reuss,David E. Reuss,Annekathrin Kratz,Annekathrin Kratz,Annika K. Wefers,Annika K. Wefers,Kristin Huang,Kristin Huang,Kristian W. Pajtler,Kristian W. Pajtler,Leonille Schweizer,Leonille Schweizer,Damian Stichel,Damian Stichel,Adriana Olar,Nils W. Engel,Nils W. Engel,Kerstin Lindenberg,Patrick N. Harter,Patrick N. Harter,Anne K. Braczynski,Anne K. Braczynski,Karl H. Plate,Karl H. Plate,Hildegard Dohmen,Boyan K. Garvalov,Roland Coras,Annett Hölsken,Ekkehard Hewer,Melanie Bewerunge-Hudler,Matthias Schick,Roger Fischer,Rudi Beschorner,Jens Schittenhelm,Ori Staszewski,Khalida Wani,Pascale Varlet,Mélanie Pagès,Petra Temming,Dietmar R. Lohmann,Florian Selt,Florian Selt,Hendrik Witt,Hendrik Witt,Till Milde,Till Milde,Olaf Witt,Olaf Witt,Eleonora Aronica,Felice Giangaspero,Elisabeth J. Rushing,Wolfram Scheurlen,Christoph Geisenberger,Christoph Geisenberger,Fausto J. Rodriguez,Albert J. Becker,Matthias Preusser,Christine Haberler,Rolf Bjerkvig,Jane Cryan,Michael A. Farrell,Martina Deckert,Jürgen Hench,Stephan Frank,Jonathan Serrano,Kasthuri Kannan,Aristotelis Tsirigos,Wolfgang Brück,Silvia Hofer,Stefanie Brehmer,Marcel Seiz-Rosenhagen,Daniel Hänggi,Volkmar Hans,Stephanie Rozsnoki,Jordan R. Hansford,Patricia Kohlhof,Bjarne Winther Kristensen,Matt Lechner,Beatriz Lopes,Christian Mawrin,Ralf Ketter,Andreas E. Kulozik,Ziad Khatib,Frank L. Heppner,Arend Koch,Anne Jouvet,Catherine Keohane,Helmut Mühleisen,Wolf Mueller,Ute Pohl,Marco Prinz,Axel Benner,Marc Zapatka,Nicholas G. Gottardo,Nicholas G. Gottardo,Pablo Hernáiz Driever,Christof M. Kramm,Hermann L. Müller,Stefan Rutkowski,Katja von Hoff,Michael C. Frühwald,Astrid Gnekow,Gudrun Fleischhack,Stephan Tippelt,Gabriele Calaminus,Camelia-Maria Monoranu,Arie Perry,Chris Jones,Thomas S. Jacques,Bernhard Radlwimmer,Marco Gessi,Torsten Pietsch,Johannes Schramm,Gabriele Schackert,Manfred Westphal,Guido Reifenberger,Guido Reifenberger,Pieter Wesseling,Pieter Wesseling,Michael Weller,Vincent Peter Collins,Ingmar Blümcke,Martin Bendszus,Jürgen Debus,Annie Huang,Nada Jabado,Paul A. Northcott,Werner Paulus,Amar Gajjar,Giles W. Robinson,Michael D. Taylor,Zane Jaunmuktane,Marina Ryzhova,Michael Platten,Andreas Unterberg,Wolfgang Wick,Matthias A. Karajannis,Michel Mittelbronn,Till Acker,Christian Hartmann,Kenneth Aldape,Ulrich Schüller,Ulrich Schüller,Rolf Buslei,Peter Lichter,Marcel Kool,Christel Herold-Mende,David W. Ellison,Martin Hasselblatt,Matija Snuderl,Sebastian Brandner,Andrey Korshunov,Andrey Korshunov,Andreas von Deimling,Andreas von Deimling,Stefan M. Pfister,Stefan M. Pfister +171 more
TL;DR: This work presents a comprehensive approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups, and shows that the availability of this method may have a substantial impact on diagnostic precision compared to standard methods.
Journal ArticleDOI
Clonal Expansions of Cd8+ T Cells Dominate the T Cell Infiltrate in Active Multiple Sclerosis Lesions as Shown by Micromanipulation and Single Cell Polymerase Chain Reaction
Holger Babbe,Axel Roers,Ari Waisman,Hans Lassmann,Norbert Goebels,Reinhard Hohlfeld,Michael Friese,Roland Schröder,Martina Deckert,Stephan Schmidt,Rivka Ravid,Klaus Rajewsky +11 more
TL;DR: Clonal composition and T cell receptor (TCR) repertoire of CD4+ and CD8+ T cells infiltrating actively demyelinating multiple sclerosis (MS) lesions were determined with unprecedented resolution at the level of single cells.
Journal ArticleDOI
Primary Central Nervous System Lymphoma: Results of a Pilot and Phase II Study of Systemic and Intraventricular Chemotherapy With Deferred Radiotherapy
Hendrik Pels,Ingo G.H. Schmidt-Wolf,Axel Glasmacher,Holger Schulz,Andreas Engert,Volker Diehl,Anton Zellner,Gabriele Schackert,Heinz Reichmann,Frank Kroschinsky,Marlies Vogt-Schaden,Gerlinde Egerer,Udo Bode,Carlo Schaller,Martina Deckert,Rolf Fimmers,Christoph Helmstaedter,Aslihan Atasoy,Thomas Klockgether,Uwe Schlegel +19 more
TL;DR: Primary chemotherapy based on high-dose MTX and ARA-C is highly efficient in PCNSL and response rate and response duration are comparable to the response rates and durations reported after combined radiotherapy and chemotherapy.
Journal ArticleDOI
Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussen's encephalitis.
Christian G. Bien,Jan Bauer,Thomas L. Deckwerth,Heinz Wiendl,Martina Deckert,Otmar D. Wiestler,Johannes Schramm,Christian E. Elger,Hans Lassmann +8 more
TL;DR: Findings indicate that a T‐cell–mediated cytotoxic reaction induces neuronal death in Rasmussen's encephalitis, and shows, for what is believed to be the first time, that a cytot toxic T‐ cell mechanism contributes to loss of neurons in human brain disease.
Journal ArticleDOI
Whole-brain radiotherapy or autologous stem-cell transplantation as consolidation strategies after high-dose methotrexate-based chemoimmunotherapy in patients with primary CNS lymphoma: results of the second randomisation of the International Extranodal Lymphoma Study Group-32 phase 2 trial
Andrés José Maria Ferreri,Kate Cwynarski,Elisa Jacobsen Pulczynski,Christopher P. Fox,Elisabeth Schorb,Paul La Rosée,Mascha Binder,Alberto Fabbri,Valter Torri,Eleonora Minacapelli,Monica Falautano,Fiorella Ilariucci,Achille Ambrosetti,Alexander Röth,Claire Hemmaway,Peter Johnson,Kim Linton,Tobias Pukrop,Jette Sønderskov Gørløv,Monica Balzarotti,Georg Hess,Ulrich Keller,Stephan Stilgenbauer,Jens Panse,Alessandra Tucci,Lorella Orsucci,Francesco Pisani,Alessandro Levis,Stefan W. Krause,Hans J. Schmoll,Bernd Hertenstein,Mathias J. Rummel,Jeffery Smith,Michael Pfreundschuh,Giuseppina Cabras,Francesco Angrilli,Maurilio Ponzoni,Martina Deckert,Letterio S. Politi,Juergen Finke,Michele Reni,Franco Cavalli,Emanuele Zucca,Gerald Illerhaus +43 more
TL;DR: The results of the second randomisation that addresses the efficacy of myeloablative chemotherapy supported by autologous stem-cell transplantation (ASCT) as an alternative to whole-brain radiotherapy (WBRT) as consolidation after high-dose-methotrexate-based chemoimmunotherapy were reported.