A
Aída Herrerías
Publications - 4
Citations - 896
Aída Herrerías is an academic researcher. The author has contributed to research in topics: Induced pluripotent stem cell & Embryonic stem cell. The author has an hindex of 4, co-authored 4 publications receiving 833 citations.
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The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming.
Athanasia D. Panopoulos,Oscar Yanes,Sergio Ruiz,Yasuyuki S. Kida,Dinh Diep,Ralf Tautenhahn,Aída Herrerías,Erika M. Batchelder,Nongluk Plongthongkum,Margaret Lutz,W. Travis Berggren,Kun Zhang,Ronald M. Evans,Gary Siuzdak,Juan Carlos Izpisua Belmonte +14 more
TL;DR: These findings are the first to globally analyze the metabolome of iPSCs, and provide mechanistic insight into a new layer of regulation involved in inducing pluripotency, and in evaluating iPSC and ESC equivalence.
Journal ArticleDOI
A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity
Sergio Ruiz,Athanasia D. Panopoulos,Aída Herrerías,Karl-Dimiter Bissig,Margaret Lutz,W. Travis Berggren,Inder M. Verma,Juan Carlos Izpisua Belmonte +7 more
TL;DR: This work shows that the characteristic cell-cycle signature of hES cells is acquired as an early event in cell reprogramming, and establishes a link that intertwines the mechanisms of cell- cycle control with the mechanisms underlying the acquisition and maintenance of ES cell identity.
Journal ArticleDOI
High-efficient generation of induced pluripotent stem cells from human astrocytes.
Sergio Ruiz,Kristen J. Brennand,Athanasia D. Panopoulos,Aída Herrerías,Fred H. Gage,Juan Carlos Izpisúa-Belmonte +5 more
TL;DR: It is shown that human astrocytes can also be reprogrammed into hiPS (ASThiPS) cells, with similar efficiencies to keratinocytes, which is currently reported to have one of the highest somatic reprogramming efficiencies.
Journal ArticleDOI
Rapid and highly efficient generation of induced pluripotent stem cells from human umbilical vein endothelial cells.
Athanasia D. Panopoulos,Sergio Ruiz,Fei Yi,Aída Herrerías,Erika M. Batchelder,Juan Carlos Izpisua Belmonte +5 more
TL;DR: Somatic cell reprogramming of human umbilical vein endothelial cells (HUVECs) is reported, yielding induced pluripotent stem (iPS) cells with the fastest kinetics, and one of the highest reprograming efficiencies for a human somatic cell to date.