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Aikun Fu

Researcher at Zhejiang University

Publications -  18
Citations -  454

Aikun Fu is an academic researcher from Zhejiang University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 10 publications receiving 180 citations. Previous affiliations of Aikun Fu include Westlake University.

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Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer

TL;DR: In this article , the authors explored the functional significance of these intratumor bacteria, primarily using a murine spontaneous breast-tumor model MMTV-PyMT, and found that depletion of intratumors significantly reduced lung metastasis without affecting primary tumor growth.
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Bacillus amyloliquefaciens SC06 alleviates the oxidative stress of IPEC-1 via modulating Nrf2/Keap1 signaling pathway and decreasing ROS production.

TL;DR: Results revealed that heme oxygenase-1 (HO-1) gene expression had a positive correlation with H2O2 induction and showed the best antioxidant capacity though modulating Nrf2 phosphorylation, resulting in decreased apoptosis and necrosis in IPEC-1.
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Probiotic Bacillus amyloliquefaciens SC06 Induces Autophagy to Protect against Pathogens in Macrophages.

TL;DR: Ba-induced autophagy was found to play a role in the elimination of intracellular bacteria when RAW264.7 cells were challenged with E. coli, indicating a protective role for probiotics via modulating macrophage immunity and highlighting a novel mechanism underlying the antibacterial activity of probiotics.
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Effects of probiotic Bacillus as a substitute for antibiotics on antioxidant capacity and intestinal autophagy of piglets.

TL;DR: Results indicate that replacing aureomycin with Ba can improve growth performance and antioxidant status of piglets via increasing antioxidant capacity and intestinal autophagy, suggesting a good potential for Ba as an alternative to antibiotics in feed.
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Intestinal microbiota and oral administration of Enterococcus faecium associated with the growth performance of new-born piglets

TL;DR: Findings suggest that oral administration of E. faecium EF1 to new-born piglets could improve the growth performance and intestinal microbiota of piglets for both suckling and weaning periods.