A
Akihiko Yoshida
Researcher at University of Tokyo
Publications - Â 243
Citations - Â 8343
Akihiko Yoshida is an academic researcher from University of Tokyo. The author has contributed to research in topics: Sarcoma & Adenocarcinoma. The author has an hindex of 41, co-authored 243 publications receiving 6187 citations. Previous affiliations of Akihiko Yoshida include Shiga University of Medical Science.
Papers
More filters
Journal ArticleDOI
Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss
Hideyuki Arita,Yoshitaka Narita,Shintaro Fukushima,Kensuke Tateishi,Yuko Matsushita,Akihiko Yoshida,Yasuji Miyakita,Makoto Ohno,V. Peter Collins,Nobutaka Kawahara,Soichiro Shibui,Koichi Ichimura +11 more
TL;DR: The data indicate that mutation of the TERT promoter is one of the major mechanisms of telomerase activation in gliomas, and suggests that they play distinct roles in the pathogenesis of oligodendroglial and astrocytic tumors.
Journal ArticleDOI
STAT6 immunohistochemistry is helpful in the diagnosis of solitary fibrous tumors.
Akihiko Yoshida,Koji Tsuta,Makoto Ohno,Masayuki Yoshida,Yoshitaka Narita,Akira Kawai,Hisao Asamura,Ryoji Kushima +7 more
TL;DR: Nuclear STAT6 immunoreactivity is a highly sensitive and specific marker of SFTs and can be helpful when diagnosis is inconclusive by conventional methods.
Journal ArticleDOI
Comprehensive histologic analysis of ALK-rearranged lung carcinomas.
Akihiko Yoshida,Koji Tsuta,Harumi Nakamura,Takashi Kohno,Fumiaki Takahashi,Hisao Asamura,Ikuo Sekine,Masashi Fukayama,Tatsuhiro Shibata,Koh Furuta,Hitoshi Tsuda +10 more
TL;DR: Multivariate analysis showed that a combination of these 2 patterns was the most powerful histologic indicator of ALK rearrangement, and histomorphology should not replace confirmatory molecular or immunohistochemical studies.
Journal ArticleDOI
KDR Activating Mutations in Human Angiosarcomas Are Sensitive to Specific Kinase Inhibitors
Cristina R. Antonescu,Akihiko Yoshida,Tianhuo Guo,Ning-En Chang,Lei Zhang,Narasimhan P. Agaram,Li-Xuan Qin,Murray F. Brennan,Samuel Singer,Robert G. Maki +9 more
TL;DR: Transient transfection of KDR mutants into COS-7 cells showed ligand-independent activation of the kinase, which was inhibited by specific KDR inhibitors, which provide a basis for the activity of vascular endothelial growth factor receptor-directed therapy in the treatment of primary and radiation-induced AS.
Journal ArticleDOI
The utility of the proposed IASLC/ATS/ERS lung adenocarcinoma subtypes for disease prognosis and correlation of driver gene alterations.
Koji Tsuta,Mitsumasa Kawago,Eisuke Inoue,Akihiko Yoshida,Fumiaki Takahashi,Hiroyuki Sakurai,Shun Ichi Watanabe,Masahiro Takeuchi,Koh Furuta,Hisao Asamura,Hitoshi Tsuda +10 more
TL;DR: The new classification of lung adenocarcinoma reflects disease prognosis, and was also associated with driver gene alterations.