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Akiko Nezu

Researcher at Osaka University

Publications -  6
Citations -  1674

Akiko Nezu is an academic researcher from Osaka University. The author has contributed to research in topics: Golgi apparatus & Chemistry. The author has an hindex of 3, co-authored 5 publications receiving 1406 citations.

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Autophagosomes form at ER–mitochondria contact sites

TL;DR: It is shown that autophagosomes form at the ER–mitochondria contact site in mammalian cells, and new insight is provided into organelle biogenesis by demonstrating that the ER-resident SNARE protein syntaxin 17 (STX17) binds ATG14 and recruits it to the ER—mitochondia contact site.
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Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy

TL;DR: Yamashita et al. show that Dnm1/Drp1-independent mitochondrial division occurs after formation of isolation membranes and in cooperation with autophagosome formation during mitophagy.
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Autophagosome–lysosome fusion in neurons requires INPP5E, a protein associated with Joubert syndrome

TL;DR: A novel role of phosphoinositide on lysosomes and an association between autophagy and neuronal disease are revealed and reveal the mechanisms underlying autophagosome–lysosome fusion process.