A
Akiko Nezu
Researcher at Osaka University
Publications - 6
Citations - 1674
Akiko Nezu is an academic researcher from Osaka University. The author has contributed to research in topics: Golgi apparatus & Chemistry. The author has an hindex of 3, co-authored 5 publications receiving 1406 citations.
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Journal ArticleDOI
Autophagosomes form at ER–mitochondria contact sites
Maho Hamasaki,Nobumichi Furuta,Atsushi Matsuda,Atsushi Matsuda,Akiko Nezu,Akitsugu Yamamoto,Naonobu Fujita,Hiroko Oomori,Takeshi Noda,Tokuko Haraguchi,Tokuko Haraguchi,Yasushi Hiraoka,Yasushi Hiraoka,Atsuo Amano,Tamotsu Yoshimori +14 more
TL;DR: It is shown that autophagosomes form at the ER–mitochondria contact site in mammalian cells, and new insight is provided into organelle biogenesis by demonstrating that the ER-resident SNARE protein syntaxin 17 (STX17) binds ATG14 and recruits it to the ER—mitochondia contact site.
Journal ArticleDOI
Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy
Shun-ichi Yamashita,Xiulian Jin,Kentaro Furukawa,Maho Hamasaki,Akiko Nezu,Hidenori Otera,Tetsu Saigusa,Tamotsu Yoshimori,Yasuyoshi Sakai,Katsuyoshi Mihara,Tomotake Kanki +10 more
TL;DR: Yamashita et al. show that Dnm1/Drp1-independent mitochondrial division occurs after formation of isolation membranes and in cooperation with autophagosome formation during mitophagy.
Journal ArticleDOI
Autophagosome–lysosome fusion in neurons requires INPP5E, a protein associated with Joubert syndrome
TL;DR: A novel role of phosphoinositide on lysosomes and an association between autophagy and neuronal disease are revealed and reveal the mechanisms underlying autophagosome–lysosome fusion process.
Journal ArticleDOI
The P4‐ATPase Drs2 interacts with and stabilizes the multisubunit tethering complex TRAPPIII in yeast
Irene Pazos,Marta Puig-Tintó,Laura Betancur,Jorge Cordero,Nereida Jiménez-Menéndez,Marc Abella,Altair C. Hernández,Ana Garcia Duran,Emi Adachi-Fernández,Carla Belmonte-Mateos,Susana Sabido-Bozo,Sébastien Tosi,Akiko Nezu,Baldo Oliva,Julien Colombelli,Todd R. Graham,Tamotsu Yoshimori,Manuel Muñiz,Maho Hamasaki,Oriol Gallego +19 more
TL;DR: In this article , P4-ATPases, a family of lipid flippases, interact with MTCs that participate in the anterograde and retrograde transport at the Golgi, such as TRAPPIII.
Posted ContentDOI
Drs2 regulates TRAPPIII in Atg9 transport: exposing the interplay of P4-ATPases and Multisubunit Tethering Complexes
Irene Pazos,Marta Puig-Tintó,Jorge Cordero,Nereida Jiménez-Menéndez,Marc Abella,Marc Abella,Ana Garcia Duran,Emi Adachi-Fernández,Carla Belmonte-Mateos,Susana Sabido-Bozo,Susana Sabido-Bozo,Altair C. Hernández,Sébastien Tosi,Akiko Nezu,Julien Colombelli,Todd R. Graham,Tamotsu Yoshimori,Manuel Muñiz,Manuel Muñiz,Maho Hamasaki,Oriol Gallego +20 more
TL;DR: In this article, P4-ATPases, a family of lipid transporters involved in the biogenesis of vesicles, interact with MTCs that participate in the anterograde and retrograde transport at the Golgi.