A
Akinori Noma
Researcher at Ritsumeikan University
Publications - 105
Citations - 4078
Akinori Noma is an academic researcher from Ritsumeikan University. The author has contributed to research in topics: Voltage clamp & Depolarization. The author has an hindex of 36, co-authored 103 publications receiving 3889 citations. Previous affiliations of Akinori Noma include Kyoto University.
Papers
More filters
Journal ArticleDOI
Molecular Characterization of the Hyperpolarization-activated Cation Channel in Rabbit Heart Sinoatrial Node
TL;DR: Results indicate that HAC4 formsI f in rabbit heart SA node, which encodes the hyperpolarization-activated cation channel (I for I h) by screening a rabbit sinoatrial node cDNA library using a fragment of rat brain cDNA.
Journal ArticleDOI
4F2 (CD98) Heavy Chain Is Associated Covalently with an Amino Acid Transporter and Controls Intracellular Trafficking and Membrane Topology of 4F2 Heterodimer
Eijiro Nakamura,Masaki Sato,Hailin Yang,Fumi Miyagawa,Masashi Harasaki,Koichi Tomita,Satoshi Matsuoka,Akinori Noma,Kazuhiro Iwai,Nagahiro Minato +9 more
TL;DR: The results indicate that the 4F2 heavy chain is associated covalently with an amino acid transporter and controls the cell surface expression as well as the membrane topology of the4F2 heterodimer.
Journal ArticleDOI
NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function
Koichiro Kuwahara,Yoshihiko Saito,Makoto Takano,Yuji Arai,Shinji Yasuno,Yasuaki Nakagawa,Nobuki Takahashi,Yuichiro Adachi,Genzo Takemura,Minoru Horie,Yoshihiro Miyamoto,Takayuki Morisaki,Shinobu Kuratomi,Akinori Noma,Hisayoshi Fujiwara,Yasunao Yoshimasa,Hideyuki Kinoshita,Rika Kawakami,Ichiro Kishimoto,Michio Nakanishi,Satoru Usami,Y. Saito,Masaki Harada,Kazuwa Nakao +23 more
TL;DR: It is demonstrated that genes encoding two ion channels that carry the fetal cardiac currents If and ICa,T, which are induced in these mice and are potentially responsible for both the cardiac dysfunction and the arrhythmogenesis, are regulated by NRSF.
Journal ArticleDOI
Reconstruction of sino-atrial node pacemaker potential based on the voltage clamp experiments.
TL;DR: It was strongly suggested that the pacemaker depolarization in the S-A node cell is mainly due to a gradual increase of iS during diastole, and that the contribution of iK is much less compared to the potassium current iK2 in the Purkinje fiber pacemakerdepolarization.
Journal ArticleDOI
Transient depolarization and spontaneous voltage fluctuations in isolated single cells from guinea pig ventricles. Calcium-mediated membrane potential fluctuations.
TL;DR: The results suggest that an oscillatory release of Ca from intracellular storage sites is the common basis underlying both the transient events (depolarization or inward current) and the spontaneous miniature fluctuations in membrane potential or current.