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Yasunao Yoshimasa
Researcher at Kyoto Prefectural University of Medicine
Publications - 47
Citations - 3201
Yasunao Yoshimasa is an academic researcher from Kyoto Prefectural University of Medicine. The author has contributed to research in topics: Insulin resistance & Diabetes mellitus. The author has an hindex of 29, co-authored 47 publications receiving 3055 citations. Previous affiliations of Yasunao Yoshimasa include University of Chicago.
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Adipocyte-Specific Expression and Regional Differences in the Adipose Tissue
Hiroaki Masuzaki,Yoshihiro Ogawa,Naohi Isse,Noriko Satoh,Taku Okazaki,Michika Shigemoto,Kiyoshi Mori,Naohisa Tamura,Kiminori Hosoda,Yasunao Yoshimasa,Hisato Jingami,Teruo Kawada,Kazuwa Nakao +12 more
TL;DR: This study is the first report of the elucidation of ob gene expression in human tissues, thereby leading to better understanding of the physiological and clinical implications of the ob gene.
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Insulin-resistant diabetes due to a point mutation that prevents insulin proreceptor processing
Yasunao Yoshimasa,Susumu Seino,Jonathan Whittaker,T. Kakehi,Atsushi Kosaki,Hideshi Kuzuya,Hiroo Imura,Graeme I. Bell,Donald F. Steiner +8 more
TL;DR: Results indicate that proteolysis of the proreceptor is necessary for its normal full insulin-binding sensitivity and signal-transducing activity and that a cellular protease that is more stringent in its specificity than trypsin is required to process the receptor precursor.
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NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function
Koichiro Kuwahara,Yoshihiko Saito,Makoto Takano,Yuji Arai,Shinji Yasuno,Yasuaki Nakagawa,Nobuki Takahashi,Yuichiro Adachi,Genzo Takemura,Minoru Horie,Yoshihiro Miyamoto,Takayuki Morisaki,Shinobu Kuratomi,Akinori Noma,Hisayoshi Fujiwara,Yasunao Yoshimasa,Hideyuki Kinoshita,Rika Kawakami,Ichiro Kishimoto,Michio Nakanishi,Satoru Usami,Y. Saito,Masaki Harada,Kazuwa Nakao +23 more
TL;DR: It is demonstrated that genes encoding two ion channels that carry the fetal cardiac currents If and ICa,T, which are induced in these mice and are potentially responsible for both the cardiac dysfunction and the arrhythmogenesis, are regulated by NRSF.
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Structural organization and chromosomal assignment of the human obese gene.
Naohi Isse,Yoshihiro Ogawa,Naohisa Tamura,Hiroaki Masuzaki,Kiyoshi Mori,Taku Okazaki,Noriko Satoh,Michika Shigemoto,Yasunao Yoshimasa,Shigeo Nishi,Kiminori Hosoda,Johji Inazawa,Kazuwa Nakao +12 more
TL;DR: The isolation and characterization of the human ob gene is reported, establishing the genetic basis for ob gene research in humans and leading to the better understanding of the molecular mechanisms underlying the ob gene.
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Diagnostic value of epinephrine test for genotyping LQT1, LQT2, and LQT3 forms of congenital long QT syndrome
Wataru Shimizu,Takashi Noda,Hiroshi Takaki,Noritoshi Nagaya,Kazuhiro Satomi,Takashi Kurita,Kazuhiro Suyama,Naohiko Aihara,Kenji Sunagawa,Shigeyuki Echigo,Yoshihiro Miyamoto,Yasunao Yoshimasa,Kazufumi Nakamura,Tohru Ohe,Jeffrey A. Towbin,Silvia G. Priori,Shiro Kamakura +16 more
TL;DR: Epinephrine infusion is a powerful test to predict the genotype of LQT1, L QT2, and LQt3 syndromes as well as to improve the clinical diagnosis of genotype-positive patients, especially those with LqT1 syndrome.