A
Akio Masuda
Researcher at Nagoya University
Publications - 88
Citations - 4049
Akio Masuda is an academic researcher from Nagoya University. The author has contributed to research in topics: RNA splicing & Exon. The author has an hindex of 33, co-authored 83 publications receiving 3516 citations.
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Journal ArticleDOI
Cutting edge: Naturally occurring soluble form of mouse toll-like receptor 4 inhibits lipopolysaccharide signaling
Kenichiro Iwami,Tetsuya Matsuguchi,Akio Masuda,Takeshi Kikuchi,Tipayaratn Musikacharoen,Yasunobu Yoshikai +5 more
TL;DR: The cloning of an alternatively spliced mouse TLR4 (mTLR4) mRNA indicates that smTLR 4 may function as a feedback mechanism to inhibit the excessive LPS responses in mouse macrophages.
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Human branch point consensus sequence is yUnAy
TL;DR: The analysis demonstrates that the human BPSs are more degenerative than the authors have expected and that they are likely to be recognized in combination with the polypyrimidine tract and/or the other splicing cis-elements.
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Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions
Shinsuke Ishigaki,Akio Masuda,Yusuke Fujioka,Yohei Iguchi,Masahisa Katsuno,Akihide Shibata,Fumihiko Urano,Gen Sobue,Kinji Ohno +8 more
TL;DR: The analysis revealed that FUS regulates alternative splicing events and transcriptions in a position-dependent manner and binding of FUS to the promoter antisense strand downregulates transcriptions of the coding strand.
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Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.
Yuan Fu,Mikako Ito,Yasunori Fujita,Masafumi Ito,Masatoshi Ichihara,Akio Masuda,Yumi Suzuki,Satoshi Maesawa,Yasukazu Kajita,Masaaki Hirayama,Ikuroh Ohsawa,Shigeo Ohta,Kinji Ohno +12 more
TL;DR: These studies suggest that hydrogen water is likely able to retard the development and progression of Parkinson's disease.
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Th2 cytokine production from mast cells is directly induced by lipopolysaccharide and distinctly regulated by c-Jun N-terminal kinase and p38 pathways.
TL;DR: It is shown that LPS induced Th2-associated cytokine production such as IL-5, IL-10, and IL-13 from mast cells and also synergistically enhanced production of these cytokines induced by IgE cross-linking.