A
Akira Uchida
Researcher at Nanyang Technological University
Publications - 60
Citations - 958
Akira Uchida is an academic researcher from Nanyang Technological University. The author has contributed to research in topics: Genome & Whole genome sequencing. The author has an hindex of 13, co-authored 57 publications receiving 778 citations. Previous affiliations of Akira Uchida include Pennsylvania State University & University of Arkansas for Medical Sciences.
Papers
More filters
Journal ArticleDOI
Nucleic acid polymerases use a general acid for nucleotidyl transfer.
Christian Castro,Eric D. Smidansky,Jamie J. Arnold,Kenneth R. Maksimchuk,Ibrahim M. Moustafa,Akira Uchida,Matthias Götte,William H. Konigsberg,Craig E. Cameron +8 more
TL;DR: The use of general acid catalysis by polymerases extends the mechanism of nucleotidyl transfer beyond that of the well-established two-metal-ion mechanism and permits manipulation of viral polymerase replication speed and/or fidelity for virus attenuation and vaccine development.
Journal ArticleDOI
Structural Mechanism and Photoprotective Function of Water-soluble Chlorophyll-binding Protein
Daisuke Horigome,Hiroyuki Satoh,Nobue Itoh,Katsuyoshi Mitsunaga,Isao Oonishi,Atsushi Nakagawa,Akira Uchida +6 more
TL;DR: The crystal structure of the WSCP-Chl complex purified from leaves of Lepidium virginicum (Virginia pepperweed) is described and it is proposed that the photoprotection mechanism may be based on the inhibition of physical contact between Chl molecules and molecular oxygen.
Journal ArticleDOI
Microbial communities in the tropical air ecosystem follow a precise diel cycle.
Elena S. Gusareva,Enzo Acerbi,Kenny J. X. Lau,Irvan Luhung,Balakrishnan N. V. Premkrishnan,Sandra Kolundžija,Rikky W. Purbojati,Anthony Wong,James N. I. Houghton,Dana Miller,Nicolas E. Gaultier,Cassie E. Heinle,Megan E. Clare,Vineeth Kodengil Vettath,Carmon Kee,Serene B. Y. Lim,Caroline Chénard,Wen Jia Phung,Kavita K. Kushwaha,Ang Poh Nee,Alexander Putra,Deepa Panicker,Koh Yanqing,Yap Zhei Hwee,Sachin R. Lohar,Mikinori Kuwata,Hie Lim Kim,Liang Yang,Akira Uchida,Daniela I. Drautz-Moses,Ana Carolina M. Junqueira,Stephan C. Schuster +31 more
TL;DR: Environmental time series revealed the existence of a large core of microbial taxa that remained invariable over 13 mo, thereby underlining the long-term robustness of the airborne community structure.
Journal ArticleDOI
Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro
Maria F. Lodeiro,Akira Uchida,Megan Bestwick,Ibrahim M. Moustafa,Jamie J. Arnold,Gerald S. Shadel,Craig E. Cameron +6 more
TL;DR: It is now clear that three promoters exist in human mtDNA, each promoter has a unique requirement for and/or response to the level of TFAM present, thus implying far greater complexity in the regulation of mammalian mitochondrial transcription than recognized to date.
Journal ArticleDOI
Oxidations of primary alcohols with a copper(II) complex as a possible galactose oxidase model
TL;DR: In this paper, the X-ray crystal structure of the copper is shown to be significantly distorted toward tetrahedral from square planar with two oxygens and two nitrogens from salicyladimine moieties.