L
Liang Yang
Researcher at Southern University of Science and Technology
Publications - 200
Citations - 10578
Liang Yang is an academic researcher from Southern University of Science and Technology. The author has contributed to research in topics: Biofilm & Pseudomonas aeruginosa. The author has an hindex of 48, co-authored 190 publications receiving 8610 citations. Previous affiliations of Liang Yang include National University of Singapore & Nanyang Technological University.
Papers
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Journal ArticleDOI
A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms
Marie Allesen-Holm,Kim Bundvig Barken,Liang Yang,Mikkel Klausen,Jeremy S. Webb,Staffan Kjelleberg,Søren Molin,Michael Givskov,Tim Tolker-Nielsen +8 more
TL;DR: Experiments with P. aeruginosa strains indicated that the extracellular DNA is generated via a mechanism which is dependent on acyl homoserine lactone and Pseudomonas quinolone signalling, as well as on flagella and type IV pili.
Journal ArticleDOI
Role of autolysin-mediated DNA release in biofilm formation of Staphylococcus epidermidis
TL;DR: Evidence is presented that extracellular DNA is important for the initial phase of biofilm development by S. epidermidis on polystyrene or glass surfaces under static or hydrodynamic conditions, and that the ext racellular DNA promotes biofilm formation of the remaining population.
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Open-Source Genomic Analysis of Shiga-Toxin–Producing E. coli O104:H4
Holger Rohde,Junjie Qin,Yujun Cui,Dongfang Li,Nicholas J. Loman,Moritz Hentschke,Wentong Chen,Fei Pu,Yangqing Peng,Junhua Li,Feng Xi,Shenghui Li,Yin Li,Zhaoxi Zhang,Xianwei Yang,Meiru Zhao,Peng Wang,Yuanlin Guan,Zhong Cen,Xiangna Zhao,Martin Christner,Robin Kobbe,Sebastian Loos,Jun Oh,Liang Yang,Antoine Danchin,George F. Gao,Yajun Song,Yingrui Li,Huanming Yang,Jian Wang,Jianguo Xu,Mark J. Pallen,Jun Wang,Martin Aepfelbacher,Ruifu Yang +35 more
TL;DR: A cluster of cases associated with a single family is reported and an open-source genomic analysis of an isolate from one member of the family is described, revealing that the outbreak strain belonged to an enteroaggregative E. coli lineage that had acquired genes for Shiga toxin 2 and for antibiotic resistance.
Journal ArticleDOI
Roles of type IV pili, flagellum-mediated motility and extracellular DNA in the formation of mature multicellular structures in Pseudomonas aeruginosa biofilms.
Kim Bundvig Barken,Sünje Johanna Pamp,Liang Yang,Morten Gjermansen,Jacob J. Bertrand,Mikkel Klausen,Michael Givskov,Cynthia B. Whitchurch,Joanne N. Engel,Tim Tolker-Nielsen +9 more
TL;DR: Evidence is presented that type IV pili, flagellum-mediated motility and quorum sensing-controlled DNA release are involved in the formation of mature multicellular structures in P. aeruginosa biofilms.
Journal ArticleDOI
An update on Pseudomonas aeruginosa biofilm formation, tolerance, and dispersal
TL;DR: The molecular mechanisms underlying the tolerance of biofilm bacteria to antimicrobial agents are beginning to be unraveled, and new knowledge has been obtained regarding the environmental cues and regulatory mechanisms involved in biofilm dispersal.