A
Akira Yamashita
Researcher at National Institute for Basic Biology, Japan
Publications - 69
Citations - 2238
Akira Yamashita is an academic researcher from National Institute for Basic Biology, Japan. The author has contributed to research in topics: Schizosaccharomyces pombe & Meiosis. The author has an hindex of 26, co-authored 63 publications receiving 2008 citations. Previous affiliations of Akira Yamashita include Graduate University for Advanced Studies & University of Tokyo.
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Journal ArticleDOI
Selective elimination of messenger RNA prevents an incidence of untimely meiosis
Yuriko Harigaya,Hirotsugu Tanaka,Hirotsugu Tanaka,Soichiro Yamanaka,Kayoko Tanaka,Yoshinori Watanabe,Yoshinori Watanabe,Chihiro Tsutsumi,Yuji Chikashige,Yasushi Hiraoka,Akira Yamashita,Masayuki Yamamoto +11 more
TL;DR: It is proposed that Mei2 turns off the DSR–Mmi1 system by sequestering Mmi1 to the dot and thereby secures stable expression of meiosis-specific transcripts.
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The Roles of Fission Yeast Ase1 in Mitotic Cell Division, Meiotic Nuclear Oscillation, and Cytokinesis Checkpoint Signaling
TL;DR: Ase1 acts as a regulatory component in the cytokine checkpoint that operates to inhibit nuclear division when the cytokinesis apparatus is perturbed, indicating that Ase1 is a dose-dependent microtubule-bundling factor.
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RNA-Assisted Nuclear Transport of the Meiotic Regulator Mei2p in Fission Yeast
TL;DR: Results indicate that meiRNA contributes to the promotion of meiosis I exclusively as a cofactor that assists nuclear transport of Mei2p.
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Importance of polyadenylation in the selective elimination of meiotic mRNAs in growing S. pombe cells
TL;DR: The critical role of polyadenylation is demonstrated in this process of selective mRNA elimination during fission yeast mitotic growth, and two‐hybrid and genetic screens revealed potential interactions between Mmi1p and proteins involved in polyadenyation.
Journal ArticleDOI
Hexanucleotide motifs mediate recruitment of the RNA elimination machinery to silent meiotic genes
Akira Yamashita,Yuichi Shichino,Hirotsugu Tanaka,Edwige Hiriart,Leila Touat-Todeschini,Aurélia Vavasseur,Da-Qiao Ding,Yasushi Hiraoka,Yasushi Hiraoka,André Verdel,Masayuki Yamamoto +10 more
TL;DR: It is shown that Mmi1 interacts with repeats of the hexanucleotide U(U/C)AAAC that are enriched in the DSR, the determinant of selective removal (DSR), which is recognized by a YTH-family RNA-binding protein, Mmi 1.