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Ala-Eddin Al Moustafa

Researcher at Qatar University

Publications -  153
Citations -  3433

Ala-Eddin Al Moustafa is an academic researcher from Qatar University. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 26, co-authored 137 publications receiving 2502 citations. Previous affiliations of Ala-Eddin Al Moustafa include Collège de France & Centre national de la recherche scientifique.

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Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis.

TL;DR: It is demonstrated that heregulin β1 induces VEGF secretion in most cancer cell lines, while no significant effect was observed in normal human mammary and bronchial primary cells.
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Identification of genes associated with head and neck carcinogenesis by cDNA microarray comparison between matched primary normal epithelial and squamous carcinoma cells.

TL;DR: This study provides the first evidence that claudin-7 and connexin 31.1 are down-regulated in head and neck squamous cell carcinomas (HNSCC) compared to normal cells, and a source of potential targets for HNSCC prevention and/or therapeutics.
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Differential regulation of tumor angiogenesis by distinct ErbB homo- and heterodimers

TL;DR: The first to examine the role of all members of the ErbB tyrosine kinase receptors (epidermal growth factor receptor), expressed singly or as paired receptor combinations, in the regulation of angiogenesis both in vitro and in vivo, reveals that EGFR/ErbB-2 and Erb B-2/ErBB-3 heterodimers are the most potent inducers of vascular endothelial growth factor mRNA expression.
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DNA Damage/Repair Management in Cancers

TL;DR: The relationship between DNA damage/repair mechanisms and cancer, and how the authors can target these pathways are discussed.
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Cerium Oxide Nanoparticle Incorporated Electrospun Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Membranes for Diabetic Wound Healing Applications.

TL;DR: The study suggests that nCeO2 incorporated PHBV membranes have strong potential to be used as wound dressings to enhance cell proliferation and vascularization and promote the healing of diabetic wounds.