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Ala-Eddin Al Moustafa
Researcher at Qatar University
Publications - 153
Citations - 3433
Ala-Eddin Al Moustafa is an academic researcher from Qatar University. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 26, co-authored 137 publications receiving 2502 citations. Previous affiliations of Ala-Eddin Al Moustafa include Collège de France & Centre national de la recherche scientifique.
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Journal ArticleDOI
Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis.
Lily Yen,Xiao-Li You,Ala-Eddin Al Moustafa,Gerald Batist,Nancy E. Hynes,Sylvie Mader,Sylvain Meloche,Moulay A. Alaoui-Jamali +7 more
TL;DR: It is demonstrated that heregulin β1 induces VEGF secretion in most cancer cell lines, while no significant effect was observed in normal human mammary and bronchial primary cells.
Journal ArticleDOI
Identification of genes associated with head and neck carcinogenesis by cDNA microarray comparison between matched primary normal epithelial and squamous carcinoma cells.
Ala-Eddin Al Moustafa,Moulay A. Alaoui-Jamali,Gerald Batist,Maite Hernandez-Perez,Corinne Serruya,Lesley Alpert,Martin J. Black,Robert Sladek,William D. Foulkes,William D. Foulkes +9 more
TL;DR: This study provides the first evidence that claudin-7 and connexin 31.1 are down-regulated in head and neck squamous cell carcinomas (HNSCC) compared to normal cells, and a source of potential targets for HNSCC prevention and/or therapeutics.
Journal ArticleDOI
Differential regulation of tumor angiogenesis by distinct ErbB homo- and heterodimers
Lily Yen,Naciba Benlimame,Zeng-Rong Nie,Dingzhang Xiao,Taiqi Wang,Ala-Eddin Al Moustafa,Hiroyasu Esumi,Julie Milanini,Nancy E. Hynes,Gilles Pagès,Moulay A. Alaoui-Jamali +10 more
TL;DR: The first to examine the role of all members of the ErbB tyrosine kinase receptors (epidermal growth factor receptor), expressed singly or as paired receptor combinations, in the regulation of angiogenesis both in vitro and in vivo, reveals that EGFR/ErbB-2 and Erb B-2/ErBB-3 heterodimers are the most potent inducers of vascular endothelial growth factor mRNA expression.
Journal ArticleDOI
DNA Damage/Repair Management in Cancers
TL;DR: The relationship between DNA damage/repair mechanisms and cancer, and how the authors can target these pathways are discussed.
Journal ArticleDOI
Cerium Oxide Nanoparticle Incorporated Electrospun Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Membranes for Diabetic Wound Healing Applications.
Robin Augustine,Anwarul Hasan,Noorunnisa Khanam Patan,Yogesh Bharat Dalvi,Ruby Varghese,Aloy Antony,Raghunath Narayanan Unni,Neelakandapillai Sandhyarani,Ala-Eddin Al Moustafa +8 more
TL;DR: The study suggests that nCeO2 incorporated PHBV membranes have strong potential to be used as wound dressings to enhance cell proliferation and vascularization and promote the healing of diabetic wounds.