Aled E. L. Roberts

TL;DR: The relative fitness of single cells and preformed aggregates during early development of Pseudomonas aeruginosa biofilms is determined and shows how free floating biofilm aggregates can have a profound local effect on biofilm development when attaching to a surface.

TL;DR: A systematic review of the most widely used in vitro biofilm systems is presented, and it is discussed why they are not always representative of the in vivo biofilms found in chronic infections.

TL;DR: It is found that the degree of spreading of an aggregate on a surface can play an important role in determining its eventual fate during biofilm development, and initially spread and initially rounded aggregates perform better when competition with surrounding unaggregated bacterial cells is low.

TL;DR: A 1,000-year-old remedy is reconstructed which kills the bacteria it was designed to treat and has shown that this activity relies on the combined activity of several antimicrobial ingredients, highlighting the scholarship of premodern doctors and the potential of ancient texts as a source of new antimicrobial agents.

TL;DR: This work describes how heterogeneity impacts on behavioral traits by evolving the strain PAO1 in biofilms grown in a synthetic sputum medium for 50 days and provides insights into the effect of allelic polymorphism on community functions in diverse P. aeruginosa populations.