A
Alejandro Berrio
Researcher at Duke University
Publications - 22
Citations - 425
Alejandro Berrio is an academic researcher from Duke University. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 6, co-authored 21 publications receiving 273 citations. Previous affiliations of Alejandro Berrio include Southern Illinois University Carbondale & University of Texas at Austin.
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Sexual fidelity trade-offs promote regulatory variation in the prairie vole brain.
TL;DR: Variation in male fidelity among monogamous prairie voles reflects differences in the expression, regulation, and epigenetic status of a vasopressin receptor that functions in spatial memory, and the trade-offs males face between fidelity and infidelity may promote heritable variation that is important for spatial memory and maintain variation in their levels of fidelity.
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Sex‐specific fitness effects of unpredictable early life conditions are associated with DNA methylation in the avian glucocorticoid receptor
Dustin R. Rubenstein,Hannah Skolnik,Alejandro Berrio,Frances A. Champagne,Steven M. Phelps,Joseph W. Solomon +5 more
TL;DR: This study is the first to show that epigenetic modifications during early life may influence the fitness of free‐living organisms adapted to unpredictable environments.
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Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function
TL;DR: The finding that the gene encoding Spike protein has been a target of both purifying and positive selection within the genome of SARS-CoV-2 is recapitulate and a test for branch-specific oversubstitution of mutations within narrow windows of the genome without reference to the genetic code is applied.
Journal ArticleDOI
Chromosomal-Level Genome Assembly of the Sea Urchin Lytechinus variegatus Substantially Improves Functional Genomic Analyses.
Phillip L Davidson,Haobing Guo,Lingyu Wang,Alejandro Berrio,He Zhang,Yue Chang,Andrew L Soborowski,David R. McClay,Guangyi Fan,Gregory A. Wray +9 more
TL;DR: Physical mapping of well-studied developmental genes onto each chromosome reveals non-random spatial distribution of distinct genes and gene families, which provides insight into how certain gene families may have evolved and are transcriptionally regulated in this species.
Journal ArticleDOI
Developmental single-cell transcriptomics in the Lytechinus variegatus sea urchin embryo.
Abdull J. Massri,Laura Greenstreet,Anton Afanassiev,Alejandro Berrio,Gregory A. Wray,Geoffrey Schiebinger,David R. McClay +6 more
TL;DR: Using scRNA-seq coupled with computational approaches, the authors studied transcriptional changes in cell states of sea urchin embryos during development to the larval stage using Waddington-OT, a computational approach to stitch together developmental time points.