Alejandro F. Barrero

TL;DR: From a marine-derived strain of the fungus Emericella variecolor, varitriol (1), varioxirane (2), dihydroterrein (3), and varixanthone (4), besides the known mold metabolites ergosterol, terrein, shamixanth one, and tajIXanthone hydrate, were identified.

TL;DR: Both theoretical and experimental evidence suggests that this titanocene-catalyzed cascade cyclization of epoxypolyenes takes place in a nonconcerted fashion via discrete carbon-centered radicals, and its end step can easily be controlled to give exocyclic double bonds by simply excluding water from the medium.

TL;DR: Results suggest that a relatively low polarity is one of the molecular requirements for the antifungal activity of sesquiterpene lactones.

TL;DR: Investigations detailed herein demonstrate that the formation of either alkoxy- or hydroxy-Ti(III) complexes considerably decreases the energy of activation for C-O bond homolysis, and two new synthetic applications of Nugent's reagent in organic chemistry are described.

TL;DR: The reaction of the Cp2TiCl complex with oxiranes leads to homolytic opening of the heterocycle with high regioselectivity as mentioned in this paper, where the resulting β-titanoxyl radical can evolve in different ways, when the epoxide reacting with CpTiCl possesses suitable unsaturated moieties such as olefins, triple bonds, carbonyls or nitriles in its structure, leading to a cyclization process.