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Aleksandra Jopek
Researcher at Poznan University of Medical Sciences
Publications - 11
Citations - 273
Aleksandra Jopek is an academic researcher from Poznan University of Medical Sciences. The author has contributed to research in topics: Lectin pathway & Mannan-binding lectin. The author has an hindex of 8, co-authored 11 publications receiving 256 citations.
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Journal ArticleDOI
Two factors of the lectin pathway of complement, l-ficolin and mannan-binding lectin, and their associations with prematurity, low birthweight and infections in a large cohort of Polish neonates.
Anna St. Swierzko,Anne P.M. Atkinson,Maciej Cedzynski,Shirley Lynn Macdonald,Agnieszka Szala,Iwona Domzalska-Popadiuk,Monika Borkowska-Klos,Aleksandra Jopek,Jerzy Szczapa,Misao Matsushita,Janusz Szemraj,Marc Turner,David C. Kilpatrick +12 more
TL;DR: It is suggested that l-ficolin participates in host defence during the perinatal period and constitute the first evidence that relative l- ficolin deficiency may contribute to the adverse consequences of prematurity.
Journal ArticleDOI
Mannan-binding lectin genotypes and genotype-phenotype relationships in a large cohort of Polish neonates.
Anna St. Swierzko,Agnieszka Szala,Maciej Cedzynski,Iwona Domzalska-Popadiuk,Monika Borkowska-Klos,Aleksandra Jopek,Jerzy Szczapa,Janusz Szemraj,Anne P.M. Atkinson,Shirley Lynn Macdonald,Marc Turner,David C. Kilpatrick +11 more
TL;DR: The data from a large cohort of neonates suggest that the current knowledge of the genetics of MBL2 is inadequate to predict serum MBL concentration and MBL-dependent lectin pathway activity in individual subjects.
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Epstein-Barr virus and human papillomavirus infections and oropharyngeal squamous cell carcinomas.
Andrzej Szkaradkiewicz,A. Kruk-Zagajewska,Marzena Wal,Aleksandra Jopek,Małgorzata Wierzbicka,Alicja Kuch +5 more
TL;DR: The results suggest that the etiopathogenesis of oropharyngeal cancers may be associated with EBV infection much more frequently than with HPV infection.
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Effects of IL-12 and IL-18 on HBcAg-specific cytokine production by CD4 T lymphocytes of children with chronic hepatitis B infection.
TL;DR: The obtained results allowed concluding that the anti-HBV activity of Th1 lymphocytes is strongly induced by IL-12+IL-18 and may contribute to viral clearance in children with chronic hepatitis B infection.
Journal ArticleDOI
Mannan-binding lectin-associated serine protease-2 (MASP-2) in a large cohort of neonates and its clinical associations.
Anna St. Swierzko,Maciej Cedzynski,Iwona Domzalska-Popadiuk,Shirley Lynn Macdonald,Monika Borkowska-Klos,Anne P.M. Atkinson,Agnieszka Szala,Aleksandra Jopek,Jens C. Jensenius,Masaya Kawakami,Jerzy Szczapa,Misao Matsushita,Janusz Szemraj,Marc Turner,David C. Kilpatrick +14 more
TL;DR: Serum MASP-2 concentrations correlated with gestational age and birthweight and were significantly lower in premature babies and other pre-term babies compared with term babies, and there was a trend towards higherMASP-1 concentrations amongst babies with infections, and no association of this SNP was apparent with prematurity, low birthweight or perinatal infections.