Alessandra Bacca

TL;DR: The frequency of the hereditary forms of pheochromocytoma/paraganglioma varies depending on the family history and the clinical presentation, and which genes should be screened first is suggested.

TL;DR: The finding that EPAS1 is involved in the sporadic presentation of the disease not only increases the percentage of PCCs/PGLs with known driver mutations, but also highlights the relevance of studying other hypoxia-related genes in apparently sporadic tumors.

TL;DR: In this paper, the authors assessed the possible vascular sources of oxidative stress, including COX-1, COX2, and nicotinamide adenine dinucleotide phosphate oxidase, as determinants of endothelial dysfunction in small arteries isolated from essential hypertensive patients or normotensive controls.

TL;DR: Substantial updated information was generated, which could simplify the diagnosis of primary aldosteronism and assist practicing physicians in optimizing treatment and follow-up of patients with one of the most common curable causes of arterial hypertension.

TL;DR: In this paper, a detailed family history (FH) and clinical, laboratory (including metanephrines), and instrumental examinations, patients were divided into three groups: a) patients with a positive FH for head and neck paragangliomas (index cases only), b) users with a negative FH and multiple HNPGLs (synchronous or metachronous) or HNGL associated with an sPGL, and c) patients who had negative fH and single HGL.