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Alessio Tempestini
Researcher at University of Florence
Publications - 23
Citations - 1210
Alessio Tempestini is an academic researcher from University of Florence. The author has contributed to research in topics: Apoptosis & Gene expression. The author has an hindex of 14, co-authored 23 publications receiving 1160 citations.
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Aponecrosis: morphological and biochemical exploration of a syncretic process of cell death sharing apoptosis and necrosis.
Lucia Formigli,Laura Papucci,Alessia Tani,Nicola Schiavone,Alessio Tempestini,G.E. Orlandini,Sergio Capaccioli,S. Zecchi Orlandini +7 more
TL;DR: It is concluded that chemically induced hypoxia produces different types of cell death depending on the intensity of the insult and on the ATP availability of the cell, and that the classic apoptosis and necrosis may represent only two extremes of a continuum of intermediate forms of cell demise.
Journal ArticleDOI
Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property.
Laura Papucci,Nicola Schiavone,Ewa Witort,Martino Donnini,Andrea Lapucci,Alessio Tempestini,Lucia Formigli,Sandra Zecchi-Orlandini,G.E. Orlandini,G. Carella,Rosario Brancato,Sergio Capaccioli +11 more
TL;DR: Evaluated the antiapoptotic effects of CoQ10 in response to apoptotic stimuli, serum starvation, antimycin A, and ceramide, which do not generate free radicals, in comparison to control, free radical-generating UVC irradiation.
Journal ArticleDOI
AUF1 Is a bcl-2 A + U-rich element-binding protein involved in bcl-2 mRNA destabilization during apoptosis.
Andrea Lapucci,Martino Donnini,Laura Papucci,Ewa Witort,Alessio Tempestini,Anna Bevilacqua,Angelo Nicolin,Gary Brewer,Nicola Schiavone,Sergio Capaccioli +9 more
TL;DR: The results indicate involvement of AUF1 in the ARE/AUBP-mediated modulation of bcl-2 mRNA decay during apoptosis and demonstrate that the 1–257-amino acid portion of p37 AUF 1 (conserved in all isoforms), containing the two RNA recognition motifs, also binds to thebcl- 2 ARE in vivo.
Journal ArticleDOI
Systemic amyloidosis: a challenge for the rheumatologist
Federico Perfetto,Alberto Moggi-Pignone,R. Livi,Alessio Tempestini,Franco Bergesio,Marco Matucci-Cerinic +5 more
TL;DR: The clinical features of amyloidosis and its rheumatic manifestations are discussed, as well as their prognosis and treatment, which are also presented.
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Flow-mediated vasodilation and carotid intima-media thickness in systemic sclerosis.
Francesca Bartoli,Jelena Blagojevic,Marzia Bacci,Ginevra Fiori,Alessio Tempestini,Maria Letizia Conforti,Serena Guiducci,I. Miniati,Mauro Di Chicco,Angela Del Rosso,Federico Perfetto,Sergio Castellani,Alberto Moggi Pignone,Marco Matucci Cerinic +13 more
TL;DR: The impairment of endothelial function and structural changes of large vessels are evident in SSc, but do not seem associated with traditional risk factors for atherosclerosis.