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G.E. Orlandini

Researcher at University of Florence

Publications -  30
Citations -  1156

G.E. Orlandini is an academic researcher from University of Florence. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 13, co-authored 28 publications receiving 1120 citations. Previous affiliations of G.E. Orlandini include University of Hamburg.

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Aponecrosis: morphological and biochemical exploration of a syncretic process of cell death sharing apoptosis and necrosis.

TL;DR: It is concluded that chemically induced hypoxia produces different types of cell death depending on the intensity of the insult and on the ATP availability of the cell, and that the classic apoptosis and necrosis may represent only two extremes of a continuum of intermediate forms of cell demise.
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Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property.

TL;DR: Evaluated the antiapoptotic effects of CoQ10 in response to apoptotic stimuli, serum starvation, antimycin A, and ceramide, which do not generate free radicals, in comparison to control, free radical-generating UVC irradiation.
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Paracrine effects of transplanted myoblasts and relaxin on post-infarction heart remodelling.

TL;DR: The beneficial effects of myoblast grafting on cardiac function are primarily dependent on the paracrine effects of transplanted cells on extracellular matrix remodelling and vascularization, and the combined treatment with myOBlast transplantation and local RLX production may be helpful in preventing deleterious cardiac remodelling.
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Morphofunctional integration between skeletal myoblasts and adult cardiomyocytes in coculture is favored by direct cell-cell contacts and relaxin treatment.

TL;DR: It is suggested that myoblasts and cardiomyocytes interact actively through gap junctions and that relaxin potentiates the intercellular coupling, and a potential role for gap junctional communication in favoring the inter cellular exchange of regulatory molecules, including Ca2+, in the modulation of myoblast differentiation is discussed.
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Osteolytic processes in human radicular cysts: morphological and biochemical results

TL;DR: In conclusion, active bone resorption may contribute significantly to the growth of these lesions within the jaws.