A
Alexander Bollenbach
Researcher at Hannover Medical School
Publications - 38
Citations - 418
Alexander Bollenbach is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Asymmetric dimethylarginine & Derivatization. The author has an hindex of 8, co-authored 34 publications receiving 246 citations.
Papers
More filters
Journal ArticleDOI
Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and homoarginine (hArg): the ADMA, SDMA and hArg paradoxes.
TL;DR: This ADMA/SDMA/hArg paradox may be solved by the assumption that not the free acids but their precursor proteins exert biological effects in the vasculature, with hArg antagonizing the effects of NG-methylated proteins.
Journal ArticleDOI
Development and validation of GC-MS methods for the comprehensive analysis of amino acids in plasma and urine and applications to the HELLP syndrome and pediatric kidney transplantation: evidence of altered methylation, transamidination, and arginase activity.
Erik Hanff,Stephan Ruben,Martin Kreuzer,Alexander Bollenbach,Arslan Arinc Kayacelebi,Anibh M. Das,Frauke von Versen-Höynck,Constantin von Kaisenberg,Dieter Haffner,Stefan Ückert,Dimitrios Tsikas +10 more
TL;DR: Gas chromatography–mass spectrometry methods for the simultaneous measurement of amino acids and their metabolites in 10-µL aliquots of human plasma and urine were developed and validated and found lower sarcosine (N-methylglycine) and higher asymmetric dimethylarginine (ADMA) plasma concentrations in HELLP syndrome women compared to healthy pregnant women, indicating altered methylation.
Journal ArticleDOI
Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings
Dimitrios Tsikas,Erik Hanff,Alexander Bollenbach,Ruan Kruger,Vu Vi Pham,Kristine Chobanyan-Jürgens,Dirk Wedekind,T Arndt,Anne Jörns,Jimmy F.P. Berbée,Hans M.G. Princen,Thomas Lücke,François Mariotti,Jean-François Huneau,Stefan Ückert,Jürgen C. Frölich,Sigurd Lenzen +16 more
TL;DR: UNOxR values were determined in preterm neonates, healthy children, and adults, in children suffering from type 1 diabetes mellitus or Duchenne muscular dystrophy, in elderly subjects suffering from chronic rheumatic diseases, type 2 Diabetes mellitus (T2DM), coronary artery disease (CAD), or peripheral arterial occlusive disease (PAOD), and in healthy young men who ingested inorganic nitrate.
Journal ArticleDOI
Effects of single and combined metformin and l-citrulline supplementation on l-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications
Erik Hanff,Patricia Hafner,Alexander Bollenbach,Ulrike Bonati,Arslan Arinc Kayacelebi,Dirk Fischer,Dimitrios Tsikas +6 more
TL;DR: In conclusion, metformin or l-citrulline supplementation to BMD patients results in remarkable antidromic changes of the AGAT and GAMT pathways.
Journal ArticleDOI
GC-MS quantification of urinary symmetric dimethylarginine (SDMA), a whole-body symmetric l-arginine methylation index.
TL;DR: An improved GC-MS method for the quantitative determination of SDMA in human urine using commercially available NG,N´G-di-[2H3]methyl-l-arginine (d6-SDMA) as internal standard is described.