Dieter Haffner

TL;DR: It is recommended that the diagnosis of XLH is based on signs of rickets and/or osteomalacia in association with hypophosphataemia and renal phosphate wasting in the absence of vitamin D or calcium deficiency.

TL;DR: A consensus statement on the application of colchicine in children and adolescents with familial Mediterranean fever was developed by caregivers from Germany, Austria, and Turkey.

TL;DR: Circulating suPAR levels are elevated in geographically and ethnically diverse patients with FSGS and do not reflect a nonspecific proinflammatory milieu, and the associations between a change in circulating suPAR with different therapeutic regimens and with remission support the role of suPAR in the pathogenesis of FSGS.

TL;DR: The pathophysiology of XLH is complex, involving a range of molecular pathways that variously contribute to different manifestations of the disease, however localised fluctuations in tissue non-specific alkaline phosphatase, pyrophosphate, calcitriol and direct effects of FGF23 have been observed to be associated with certain manifestations.

TL;DR: A team of experts including pediatric nephrologists and renal geneticists from the International Pediatric Nephrology Association, a renal pathologist, and an adult nephrologyist have now developed comprehensive clinical practice recommendations on the diagnosis and management of steroid-resistant nephrotic syndrome in children.