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Alexander Heckel
Researcher at Goethe University Frankfurt
Publications - 67
Citations - 4897
Alexander Heckel is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 29, co-authored 54 publications receiving 4536 citations. Previous affiliations of Alexander Heckel include ETH Zurich & University of Bonn.
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Journal ArticleDOI
Biologically active molecules with a "light switch".
Günter Mayer,Alexander Heckel +1 more
TL;DR: This review summarizes new developments of the last five years and deals with "small molecules", proteins, and nucleic acids which can either be irreversibly activated with light (these compounds are referred to as "caged compounds") or reversibly switched between an active and an inactive state.
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Light-Controlled Tools
TL;DR: This Review will focus on developments over the last six years and includes discussions on the underlying technologies as well as their applications.
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TADDOLs, Their Derivatives, and TADDOL Analogues: Versatile Chiral Auxiliaries
TL;DR: TADDOLs are the most effective doping agents known for phase transformations of achiral (nematic) into chiral (cholesteric) liquid crystals and show further unusual characteristics that make them useful for applications in material science and supramolecular chemistry.
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Biologisch aktive Moleküle mit “Lichtschalter”
Günter Mayer,Alexander Heckel +1 more
TL;DR: In this article, aktive Verbindungen, die auf Licht reagieren, bieten experimentelle Moglichkeiten, which sonst nur sehr schwierig zu realisieren sind.
Journal ArticleDOI
Activity-dependent spatially localized miRNA maturation in neuronal dendrites
Sivakumar Sambandan,Güney Akbalik,Lisa Kochen,Jennifer S. Rinne,Josefine Kahlstatt,Caspar Glock,Georgi Tushev,Beatriz Alvarez-Castelao,Alexander Heckel,Erin M. Schuman,Erin M. Schuman +10 more
TL;DR: An inducible fluorescent probe was developed to explore whether the maturation of a miRNA could be regulated in space and time in neurons and found it was associated with a spatially restricted reduction in the protein synthesis of a target mRNA.