Alexandra I. Barsdorf

TL;DR: In patients with transthyretin amyloid cardiomyopathy, tafamidis was associated with reductions in all‐cause mortality and cardiovascular‐related hospitalizations and reduced the decline in functional capacity and quality of life as compared with placebo.

TL;DR: In this paper , the best practice recommendations for clinical study sponsors or their designee for conducting user acceptance testing with support from eCOA providers to ensure data quality and enhance operational efficiency of the e-COA system are presented.

TL;DR: In this paper , the best practice recommendations for clinical study sponsors or their designee for conducting user acceptance testing with support from eCOA providers to ensure data quality and enhance operational efficiency of the e-COA system are presented.

TL;DR: The ISPOR Task Force on measurement comparability between modes of data collection for patient-reported outcome measures (PROMs) has updated the good practice recommendations from the 2009 ISPOR electronic patientreported outcome and 2014 patient reported outcome mixed modes Good Research Practices Task Force reports in light of accumulated evidence of comparison among different modes of PROM data collection as discussed by the authors .

TL;DR: The clinical scoring algorithm for the POMAQ was developed and refined to reflect clinically relevant patient behaviors identified by expert review and to achieve maximal concordance of classifications across experts.