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Alexandre de Fátima Cobre
Researcher at Federal University of Paraná
Publications - 25
Citations - 513
Alexandre de Fátima Cobre is an academic researcher from Federal University of Paraná. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 4, co-authored 14 publications receiving 178 citations.
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Journal ArticleDOI
Systematic review with meta-analysis of the accuracy of diagnostic tests for COVID-19.
Beatriz Böger,Mariana Millan Fachi,Raquel de Oliveira Vilhena,Alexandre de Fátima Cobre,Fernanda S. Tonin,Roberto Pontarolo +5 more
TL;DR: RT-PCR remains the gold standard for the diagnosis of COVID-19 in sputum samples and the combination of different diagnostic tests is highly recommended to achieve adequate sensitivity and specificity.
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Occurrence of antibiotics and antibiotic resistant bacteria in subtropical urban rivers in Brazil
Beatriz Böger,Monica Surek,Raquel de Oliveira Vilhena,Mariana Millan Fachi,Allan M. Junkert,Josiane Mmf Santos,Eric Luiz Domingos,Alexandre de Fátima Cobre,Danilo Raul Ossufo Momade,Roberto Pontarolo +9 more
TL;DR: Investigation of the presence of antibiotics of different classes and associated resistant bacteria, in water samples taken from urban river waters in Curitiba, Brazil found antibiotics came from domestic effluents and may be contributing to the spread of bacterial resistance.
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Risk factors associated with delay in diagnosis and mortality in patients with COVID-19 in the city of Rio de Janeiro, Brazil
Alexandre de Fátima Cobre,Beatriz Böger,Mariana Millan Fachi,Raquel de Oliveira Vilhena,Eric Luiz Domingos,Fernanda S. Tonin,Roberto Pontarolo +6 more
TL;DR: Delays in diagnosis and risk factors for death from COVID-19 were associated with male gender, age under 60 years, and patients living in regions with lower SDI, and delays superior to eight days to diagnosis increased mortality rates.
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Diagnosis and prediction of COVID-19 severity: can biochemical tests and machine learning be used as prognostic indicators?
Alexandre de Fátima Cobre,Dile Pontarolo Stremel,Guilhermina Rodrigues Noleto,Mariana Millan Fachi,Monica Surek,Astrid Wiens,Fernanda S. Tonin,Roberto Pontarolo +7 more
TL;DR: In this article, the authors used Artificial Neural Networks (ANN), decision trees (DT), partial least squares discriminant analysis (PLS-DA), and K nearest neighbor algorithm (KNN) models to predict positive and negative patients with COVID-19.
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Chemical composition, cytotoxicity, and antibacterial activity of propolis from Africanized honeybees and three different Meliponini species
Monica Surek,Mariana Millan Fachi,Alexandre de Fátima Cobre,Favízia Freitas de Oliveira,Roberto Pontarolo,Amanda Rabello Crisma,Wesley M. Souza,Karina Bettega Felipe +7 more
TL;DR: Propolis could be a source of antineoplastics and antibiotics and may reduce the occurrence of doxorubicin and gentamicin related adverse effects, resistance, or both.