Raquel de Oliveira Vilhena

TL;DR: RT-PCR remains the gold standard for the diagnosis of COVID-19 in sputum samples and the combination of different diagnostic tests is highly recommended to achieve adequate sensitivity and specificity.

TL;DR: Investigation of the presence of antibiotics of different classes and associated resistant bacteria, in water samples taken from urban river waters in Curitiba, Brazil found antibiotics came from domestic effluents and may be contributing to the spread of bacterial resistance.

TL;DR: A HPLC-MS/MS method capable of simultaneously determining levodopa, carbidopa, entacapone, tolcapone, 3-O-methyldopa and dopamine in human plasma was developed and validated and successfully applied in plasma patients with Parkinson's disease using Stalevo®.

TL;DR: The results indicated that this new method using HILIC mode and LC-MS/MS for simultaneous determination of carbidopa, levodopa, and its metabolites in human plasma is suitable for therapeutic drug monitoring in Parkinson's disease patients.

TL;DR: Delays in diagnosis and risk factors for death from COVID-19 were associated with male gender, age under 60 years, and patients living in regions with lower SDI, and delays superior to eight days to diagnosis increased mortality rates.