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Ali M. Ardekani
Researcher at Avicenna Research Institute
Publications - 48
Citations - 5803
Ali M. Ardekani is an academic researcher from Avicenna Research Institute. The author has contributed to research in topics: Cancer & Ovarian cancer. The author has an hindex of 17, co-authored 47 publications receiving 5538 citations. Previous affiliations of Ali M. Ardekani include Academic Center for Education, Culture and Research & University of South Florida.
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Journal ArticleDOI
Use of proteomic patterns in serum to identify ovarian cancer
Emanuel F. Petricoin,Ali M. Ardekani,Ben A. Hitt,Peter J. Levine,Vincent A. Fusaro,Seth M. Steinberg,Gordon B. Mills,Charles B. Simone,David A. Fishman,Elise C. Kohn,Lance A. Liotta +10 more
TL;DR: A bioinformatics tool was developed and used to identify proteomic patterns in serum that distinguish neoplastic from non-neoplastic disease within the ovary, justifying a prospective population-based assessment of proteomic pattern technology as a screening tool for all stages of ovarian cancer in high-risk and general populations.
Journal ArticleDOI
Serum Proteomic Patterns for Detection of Prostate Cancer
Emanuel F. Petricoin,David K. Ornstein,Cloud P. Paweletz,Ali M. Ardekani,Paul S. Hackett,Ben A. Hitt,Alfredo Velassco,Christian Trucco,Laura Wiegand,Kamillah Wood,Charles B. Simone,Peter J. Levine,W. Marston Linehan,Michael R. Emmert-Buck,Seth M. Steinberg,Elise C. Kohn,Lance A. Liotta +16 more
TL;DR: If validated in future series, serum proteomic pattern diagnostics may be of value in deciding whether to perform a biopsy on a man with an elevated PSA level.
Journal ArticleDOI
Use of proteomic patterns in serum to identify ovarian Cancer
Emanuel F. Petricoin,Ali M. Ardekani,Ben A. Hitt,Peter J. Levine,Vincent A. Fusaro,Seth M. Steinberg,Gordon B. Mills,Charles B. Simone,David A. Fishman,Elise C. Kohn,Lance A. Liotta +10 more
TL;DR: The ability of proteomic patterns to detect the presence of ovarian cancer had a sensitively of 100%, a specificity of 95%, and a positive predictive value of 94%.
Journal Article
The Role of MicroRNAs in Human Diseases
TL;DR: MicroRNAs (miRNAs) are short RNA molecules which bind to target mRNAs, resulting in translational repression and gene silencing and are found in all eukaryotic cells.
Journal ArticleDOI
Clinical potential of proteomics in the diagnosis of ovarian cancer.
TL;DR: Serum proteomic pattern analysis might be applied ultimately in medical screening clinics, as a supplement to the diagnostic work-up and evaluation of patients with ovarian cancer.