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Ali Ouaissi
Researcher at University of Montpellier
Publications - 81
Citations - 2895
Ali Ouaissi is an academic researcher from University of Montpellier. The author has contributed to research in topics: Trypanosoma cruzi & Leishmania infantum. The author has an hindex of 32, co-authored 81 publications receiving 2757 citations. Previous affiliations of Ali Ouaissi include French Institute of Health and Medical Research & Instituto de Biologia Molecular e Celular.
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Axenically Grown Amastigotes of Leishmania infantum Used as an In Vitro Model To Investigate the Pentavalent Antimony Mode of Action
TL;DR: Results were consistent with the hypothesis of an intramacrophagic metabolic conversion of Sb(V) into trivalent compounds, which in turn became readily toxic to the Leishmania amastigote stage.
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Antimonial-mediated DNA fragmentation in Leishmania infantum amastigotes.
TL;DR: The results demonstrate that the antileishmanial toxicity of Sb(III) antimonials is associated with parasite oligonucleosomal DNA fragmentation, indicative of the occurrence of late events in the overall process of apoptosis.
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The Trypanosoma cruzi Tc52-released protein induces human dendritic cell maturation, signals via Toll-like receptor 2, and confers protection against lethal infection.
Ali Ouaissi,Eliane Guilvard,Yves Delneste,Gersende Caron,Giovanni Magistrelli,Nathalie Herbault,Nathalie Thieblemont,Pascale Jeannin +7 more
TL;DR: It is reported that immunization with Tc52 protects mice in vivo against lethal infection with T. cruzi, and the immune protection data suggest that Tc 52 is among candidate molecules that may be used to design an optimal multicomponent vaccine to control T. cruiser infection.
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Advances and perspectives in Leishmania cell based drug-screening procedures.
TL;DR: This review will focus on available methodologies for direct drug screening purposes against the mammalian stage of the parasite, with emphasis on the future developments that could improve sensitivity, reliability, versatility and the throughput of the intracellular model screening.
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High Histone Deacetylase 7 (HDAC7) Expression Is Significantly Associated with Adenocarcinomas of the Pancreas
Mehdi Ouaissi,Igor Sielezneff,Ricardo Silvestre,Bernard Sastre,Jean-Paul Bernard,Jean-Paul Bernard,Joelle Simony Lafontaine,Marie José Payan,Laetitia Dahan,Nicolas Pirro,Jean Francois Seitz,Eric Mas,Dominique Lombardo,Ali Ouaissi,Ali Ouaissi +14 more
TL;DR: Evaluating the expression levels of members of class I (HDAC1, 2, 3, 4, 5, 6, and 7), and class III in a set of surgically resected pancreatic tissues showed alteration of HDACs gene expression in pancreatic cancer.