A
Alison W. Gagnon
Researcher at Aventis Pharma
Publications - 4
Citations - 178
Alison W. Gagnon is an academic researcher from Aventis Pharma. The author has contributed to research in topics: Signal peptide & G protein-coupled receptor. The author has an hindex of 4, co-authored 4 publications receiving 173 citations.
Papers
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Journal ArticleDOI
Contribution of in vivo models of thrombosis to the discovery and development of novel antithrombotic agents.
TL;DR: Animal models will play a primary role in the discovery and characterization of the novel antithrombotic agents that will provide safe and effective pharmacological treatment for life-threatening thrombosis diseases.
Journal ArticleDOI
Cloning and characterization of a novel regulator of G protein signalling in human platelets.
TL;DR: Full-length cloning of this novel RGS, which is now term RGS18, demonstrates that this transcript is predicted to encode a 235-amino acid protein that is most closely related to RGS5 (46% identity) and that has approximately 30-40% identity to other RGS proteins.
Journal ArticleDOI
Molecular cloning and functional characterization of a human liver vasoactive intestinal peptide receptor
TL;DR: These studies indicate that this cDNA encodes a human liver VIP receptor which is functionally coupled to the activation of adenylyl cyclase in transfected COS cells, as evidenced by a dose-dependent increase in intracellular cAMP accumulation.
Patent
Nucleic acids encoding a regulator of a g protein signaling, rgs18, and uses thereof
Murray David L,Alison W. Gagnon +1 more
TL;DR: In this paper, the authors proposed a method for the detection of activators or inhibitors of RGS18 polypeptides, which are abundantly expressed in platelets and comprise a novel RGS domain (RGS18 domain).